When Sirtuins and NF-κB Collide

Research output: Contribution to journalArticlepeer-review


Both the sirtuins and certain transcription factors of the NF-κB/Rel family control aging-associated changes in gene expression. Kawahara et al. (2009) now show a requirement in mice for the sirtuin SIRT6 in dampening NF-κB-dependent gene expression, thus unveiling a potential link between inflammation, aging, and metabolism.

Original languageEnglish
Pages (from-to)19-21
Number of pages3
Issue number1
Publication statusPublished - Jan 9 2009

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)


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