IL P.E.V. DA STIMOLAZIONE RETINICA CENTRALE E PERIFERICIA: UN NUOVO METODO DI STIMOLAZIONE PER LA DIAGNOSI DI SCLEROSI MULTIPLA

Anatomo-physiological data indicate that the axons originating from the fovea are smaller and have a lower conduction velocity than those originating from the retinal periphery. This explains the distinct difference in latency between central and peripheral visual evoked potentials in the normal subject. Personal data confirm the high incidence of involvement of the foveal fibers in multiple sclerosis, in accordance with psychophysical findings reported by Bodis-Wollner (1976) and Regan et al (1977) who demonstrated a selective loss of contrast sensitivity in the high medium spatial frequencies, particularly perceptible for central and paracentral vision (for further details see Rossini et al, 1979).