TERAPIA CON VIGABATRIN: TOLLERABILITA IN 32 PAZIENTI ADULTI

M. T. Faedda; A. T. Giallonardo; P. Quarato; A. Francia; A. Iudice; S. Fabri; M. Manfredi

TERAPIA CON VIGABATRIN: TOLLERABILITA IN 32 PAZIENTI ADULTI

Translated title of the contribution: Vigabatrin therapy: Tolerability in 32 adult patients

M. T. Faedda, A. T. Giallonardo, P. Quarato, A. Francia, A. Iudice, S. Fabri, M. Manfredi

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Abstract

Thirtytwo adult patients (16 females and 16 males, aged from 20 to 59 years) with refractory partial epilepsy entered a single blind study with Vigabatrin (VGB) as add on therapy. There were 19 drop outs. Thirteen patients continued the study, with a follow up of 6 years in 7 and of 3 years in 6. The number of seizures decreased by 100% in one patient, by 70 to 83.3% in four patients, by 50 to 64.28% in three patients and by 50% in five. The side effects were: drowsiness (13 pt), weight gain or appetite (12 pt), oedema (8 pt), sual disturbances (4 pt), appetite gain (3 pt), constipation (3 pt), ataxia (2 pt), delusional episode (1 pt), gastralgia (1 pt).

Translated title of the contribution	Vigabatrin therapy: Tolerability in 32 adult patients
Original language	Italian
Pages (from-to)	271-272
Number of pages	2
Journal	Bollettino - Lega Italiana contro l'Epilessia
Issue number	79-80
Publication status	Published - 1992

ASJC Scopus subject areas

Clinical Neurology

Cite this

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title = "TERAPIA CON VIGABATRIN: TOLLERABILITA IN 32 PAZIENTI ADULTI",

abstract = "Thirtytwo adult patients (16 females and 16 males, aged from 20 to 59 years) with refractory partial epilepsy entered a single blind study with Vigabatrin (VGB) as add on therapy. There were 19 drop outs. Thirteen patients continued the study, with a follow up of 6 years in 7 and of 3 years in 6. The number of seizures decreased by 100% in one patient, by 70 to 83.3% in four patients, by 50 to 64.28% in three patients and by 50% in five. The side effects were: drowsiness (13 pt), weight gain or appetite (12 pt), oedema (8 pt), sual disturbances (4 pt), appetite gain (3 pt), constipation (3 pt), ataxia (2 pt), delusional episode (1 pt), gastralgia (1 pt).",

author = "Faedda, {M. T.} and Giallonardo, {A. T.} and P. Quarato and A. Francia and A. Iudice and S. Fabri and M. Manfredi",

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T1 - TERAPIA CON VIGABATRIN

T2 - TOLLERABILITA IN 32 PAZIENTI ADULTI

AU - Faedda, M. T.

AU - Giallonardo, A. T.

AU - Quarato, P.

AU - Francia, A.

AU - Iudice, A.

AU - Fabri, S.

AU - Manfredi, M.

PY - 1992

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AB - Thirtytwo adult patients (16 females and 16 males, aged from 20 to 59 years) with refractory partial epilepsy entered a single blind study with Vigabatrin (VGB) as add on therapy. There were 19 drop outs. Thirteen patients continued the study, with a follow up of 6 years in 7 and of 3 years in 6. The number of seizures decreased by 100% in one patient, by 70 to 83.3% in four patients, by 50 to 64.28% in three patients and by 50% in five. The side effects were: drowsiness (13 pt), weight gain or appetite (12 pt), oedema (8 pt), sual disturbances (4 pt), appetite gain (3 pt), constipation (3 pt), ataxia (2 pt), delusional episode (1 pt), gastralgia (1 pt).

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TERAPIA CON VIGABATRIN: TOLLERABILITA IN 32 PAZIENTI ADULTI

Abstract

ASJC Scopus subject areas

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