Use of Dithiothreitol to Dislodge Bacteria From the Biofilm on an Aortic Valve in the Operating Theatre: A Case of Infective Endocarditis Caused by Staphylococcus aureus and Proteus mirabilis

Sara G. Rimoldi; Elena De Vecchi; Cristina Pagani; Agostino Zambelli; Annamaria Di Gregorio; Enrica Bosisio; Paolo Vanelli; Roberto Scrofani; Maria R. Gismondo; Giovanni Cagnoni; Carlo Antona

doi:10.1016/j.athoracsur.2016.03.023

Use of Dithiothreitol to Dislodge Bacteria From the Biofilm on an Aortic Valve in the Operating Theatre: A Case of Infective Endocarditis Caused by Staphylococcus aureus and Proteus mirabilis

Sara G. Rimoldi, Elena De Vecchi, Cristina Pagani, Agostino Zambelli, Annamaria Di Gregorio, Enrica Bosisio, Paolo Vanelli, Roberto Scrofani, Maria R. Gismondo, Giovanni Cagnoni, Carlo Antona

IRCCS Istituto Ortopedico Galeazzi

Research output: Contribution to journal › Article › peer-review

Abstract

This is the first reported case of 2 biofilm-producing bacteria, Staphylococcus aureus and Proteus mirabilis, identified from an aortic valve using an innovative device with dithiothreitol solution, able to dislodge bacterial biofilm. The method is usable in the operating theatre and recommended in infective endocarditis nonresponders to empiric therapy.

Original language	English
Pages (from-to)	e357-e359
Journal	Annals of Thoracic Surgery
Volume	102
Issue number	4
DOIs	https://doi.org/10.1016/j.athoracsur.2016.03.023
Publication status	Published - Oct 1 2016

ASJC Scopus subject areas

Surgery
Pulmonary and Respiratory Medicine
Cardiology and Cardiovascular Medicine

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10.1016/j.athoracsur.2016.03.023

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Rimoldi, S. G., De Vecchi, E., Pagani, C., Zambelli, A., Di Gregorio, A., Bosisio, E., Vanelli, P., Scrofani, R., Gismondo, M. R., Cagnoni, G., & Antona, C. (2016). Use of Dithiothreitol to Dislodge Bacteria From the Biofilm on an Aortic Valve in the Operating Theatre: A Case of Infective Endocarditis Caused by Staphylococcus aureus and Proteus mirabilis. Annals of Thoracic Surgery, 102(4), e357-e359. https://doi.org/10.1016/j.athoracsur.2016.03.023

Use of Dithiothreitol to Dislodge Bacteria From the Biofilm on an Aortic Valve in the Operating Theatre : A Case of Infective Endocarditis Caused by Staphylococcus aureus and Proteus mirabilis. / Rimoldi, Sara G.; De Vecchi, Elena; Pagani, Cristina et al.

In: Annals of Thoracic Surgery, Vol. 102, No. 4, 01.10.2016, p. e357-e359.

Research output: Contribution to journal › Article › peer-review

Rimoldi, SG, De Vecchi, E, Pagani, C, Zambelli, A, Di Gregorio, A, Bosisio, E, Vanelli, P, Scrofani, R, Gismondo, MR, Cagnoni, G & Antona, C 2016, 'Use of Dithiothreitol to Dislodge Bacteria From the Biofilm on an Aortic Valve in the Operating Theatre: A Case of Infective Endocarditis Caused by Staphylococcus aureus and Proteus mirabilis', Annals of Thoracic Surgery, vol. 102, no. 4, pp. e357-e359. https://doi.org/10.1016/j.athoracsur.2016.03.023

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abstract = "This is the first reported case of 2 biofilm-producing bacteria, Staphylococcus aureus and Proteus mirabilis, identified from an aortic valve using an innovative device with dithiothreitol solution, able to dislodge bacterial biofilm. The method is usable in the operating theatre and recommended in infective endocarditis nonresponders to empiric therapy.",

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Use of Dithiothreitol to Dislodge Bacteria From the Biofilm on an Aortic Valve in the Operating Theatre: A Case of Infective Endocarditis Caused by Staphylococcus aureus and Proteus mirabilis

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