@article{3e97cf0a899546e08cfcefee01f6d53a,
title = "Use of critical care resources during the first 2 weeks (February 24–March 8, 2020) of the Covid-19 outbreak in Italy: Annals of Intensive Care",
abstract = "Background: A Covid-19 outbreak developed in Lombardy, Veneto and Emilia-Romagna (Italy) at the end of February 2020. Fear of an imminent saturation of available ICU beds generated the notion that rationing of intensive care resources could have been necessary. Results: In order to evaluate the impact of Covid-19 on the ICU capacity to manage critically ill patients, we performed a retrospective analysis of the first 2 weeks of the outbreak (February 24–March 8). Data were collected from regional registries and from a case report form sent to participating sites. ICU beds increased from 1545 to 1989 (28.7%), and patients receiving respiratory support outside the ICU increased from 4 (0.6%) to 260 (37.0%). Patients receiving respiratory support outside the ICU were significantly older [65 vs. 77 years], had more cerebrovascular (5.8 vs. 13.1%) and renal (5.3 vs. 10.0%) comorbidities and less obesity (31.4 vs. 15.5%) than patients admitted to the ICU. PaO2/FiO2 ratio, respiratory rate and arterial pH were higher [165 vs. 244; 20 vs. 24 breath/min; 7.40 vs. 7.46] and PaCO2 and base excess were lower [34 vs. 42 mmHg; 0.60 vs. 1.30] in patients receiving respiratory support outside the ICU than in patients admitted to the ICU, respectively. Conclusions: Increase in ICU beds and use of out-of-ICU respiratory support allowed effective management of the first 14 days of the Covid-19 outbreak, avoiding resource rationing. {\textcopyright} 2020, The Author(s).",
keywords = "Acute respiratory failure, COVID-19, ICU, Non-invasive ventilation, Rationing, adult, aged, alkalosis, arterial pH, Article, assisted ventilation, breathing rate, comorbidity, continuous positive airway pressure, controlled study, coronavirus disease 2019, critically ill patient, female, follow up, hospital admission, human, intensive care, intensive care unit, Italy, major clinical study, male, mortality, noninvasive ventilation, obesity, oxygen therapy, priority journal, register, retrospective study",
author = "{COVID-19 Northern Italian ICU Network} and T. Tonetti and G. Grasselli and A. Zanella and G. Pizzilli and R. Fumagalli and S. Piva and L. Lorini and G. Iotti and G. Foti and S. Colombo and L. Vivona and S. Rossi and M. Girardis and A. Campagna and M. Cecconi and F. Locatelli and M. Bartoletti and M. Giannella and P. Viale and M. Antonelli and S. Nava and A. Pesenti and V.M. Ranieri and G. Aldegheri and E. Beretta and S. Bonazzi and L. Carnevale and G. Castelli and D. Chiumello and S. Greco and G. Landoni and T. Langer and A. Lombardo and G. Marino and G. Merli and D. Merlo and F. Mojoli and M. Raimondi and M. Riccio and E. Storti and G. Vitale and M. Saia and M. Baiocchi and M. Benedetto and F. Caramelli and C. Martino and R.M. Melotti and F. Moro and E. Pierucci and A. Zanoni",
note = "Cited By :3 Export Date: 11 March 2021 Correspondence Address: Tonetti, T.; Alma Mater Studiorum, Via Massarenti, Italy; email: tommaso.tonetti@unibo.it Funding text 1: Dr. Cecconi reports personal fees from Edwards Lifesciences, personal fees from Directed Systems, personal fees from Cheetah Medical, outside the present work. Dr. Grasselli reports personal fees and non-financial support from Getinge, personal fees and non-financial support from Biotest, personal fees from Thermofisher, grants and personal fees from Fisher&Paykel, personal fees from Draeger Medical, outside the present work. Dr. Iotti reports personal fees from Hamilton Medical, personal fees from Getinge Italia, personal fees from Eurosets, personal fees from Intersurgical, personal fees from Burke & Burke, outside the present work. Dr. Pesenti reports personal fees from Maquet, personal fees from Novalung/Xenios, personal fees from Baxter, personal fees from Boehringer Ingelheim, outside the present work. Dr. Zanella has a patent ES2732104 licensed to AW Technologies, a patent US2017348472 licensed to Fresenius, and a patent US2017224898 licensed to Fresenius.",
year = "2020",
doi = "10.1186/s13613-020-00750-z",
language = "English",
volume = "10",
journal = "Ann. Intensive Care",
issn = "2110-5820",
publisher = "Springer Science and Business Media Deutschland GmbH",
number = "1",
}