Genetic abnormalities of pulmonary surfactant were identified by DNA sequence analysis in 14 (12 full-term, 2 preterm) of 17 newborn infants with fatal respiratory distress of unknown etiology. Deficiency of adenosine triphosphate-binding cassette protein, member A3 (n = 12) was a more frequent cause of this phenotype than deficiency of surfactant protein B (n = 2).
|Journal||Journal of Pediatrics|
|Publication status||Published - Jun 2007|
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health