Studio del carcinoma prostatico mediante ecografia e Risonanza Magnetica con bobina di superficie dedicata

Translated title of the contribution: Ultrasonography and "dedicated" surface coil MRI of prostatic carcinoma

Paolo Preziosi, Michele Mulas, Manlio Guazzaroni, Luca Gagliarducci, Enrico Cruciani, Criselda Santacroce, Antonio Orlacchio

Research output: Contribution to journalArticlepeer-review


We investigated the role of an experimental surface coil for low field (0.2 T) MRI of prostatic gland carcinoma; the study was performed comparing MRI with US findings and with bioptic and pathologic results. To this purpose, 16 patients with prostatic cancer suspected at US and demonstrated with US-guided biopsy, were examined with low intensity field (0.2 T) MRI performed with a dedicated saddle-shaped coil and a body coil. This experimental surface coil with perineal application is used to study the prostatic gland with low field MR equipment where no transrectal probe is available. We analyzed the results of this study and found that, in all patients but one, the neoplastic lesions exhibited low signal intensity on T2-weighted images, while the normal gland was hyperintense. Six patients underwent radical prostatectomy and diagnostic imaging findings were correlated with pathologic findings obtained with whole mount specimens and serial histologic slides. The number of tumor foci, their site and size, and stromal reaction were studied on T2-weighted images; the typical low signal intensity was absent in one of 16 patients, in which case the microscopic exam of pathologic specimens showed extensive tumor spread with infiltration of perineural lympathic vessels, with neither nodular patterns nor stromal reactions. The correlation between MR findings and the whole mount specimens (n = 6) demonstrated MR underestimation of tumor spread. In our opinion, this technique is useful for the detection and characterization of prostatic lesions, in spite of the presence of isointense lesions and the risk of underestimating the disease, especially to the prostatic capsule. To conclude, the dedicated surface coil can improve the diagnostic accuracy of low field MRI.

Translated title of the contributionUltrasonography and "dedicated" surface coil MRI of prostatic carcinoma
Original languageItalian
Pages (from-to)752-757
Number of pages6
JournalRadiologia Medica
Issue number6
Publication statusPublished - Dec 1996

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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