Type 2 diabetes mellitus and atrial fibrillation: From mechanisms to clinical practice

Marijana Tadic, Cesare Cuspidi

Research output: Contribution to journalArticlepeer-review


Summary Type 2 diabetes mellitus is one of the most common chronic conditions and its prevalence has increased continuously over the past decades, primarily due to the obesity epidemic. Atrial fibrillation (AF) is the most frequent sustained cardiac arrhythmia in clinical practice and is associated with increased cardiovascular and cerebrovascular morbidity and mortality. Recent studies have shown that patients with diabetes have an increased risk of AF. However, the results about the relationship between diabetes and AF are still conflicting. Mechanisms that are responsible for an association between diabetes and AF, as well as the adequate treatment of AF in patients with diabetes, are still insufficiently studied. The aim of this review is to summarize the current knowledge of mechanisms that connect AF and diabetes, the clinical studies that include patients with both conditions, and the treatment options in modern pharmacology.

Original languageEnglish
Article number806
Pages (from-to)269-276
Number of pages8
JournalArchives of Cardiovascular Diseases
Issue number4
Publication statusPublished - Apr 1 2015


  • Atrial fibrillation
  • Clinical studies
  • Mechanisms
  • Treatment
  • Type 2 diabetes mellitus

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Medicine(all)


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