Two sensitive PCR-based methods for detection of hepatitis B virus variants associated with reduced susceptibility to lamivudine

Marchelle I. Allen, Josee Gauthier, Manon DesLauriers, Eric J. Bourne, Kevin M. Carrick, Fausto Baldanti, Lisa L. Ross, Michael W. Lutz, Lynn D. Condreay

Research output: Contribution to journalArticlepeer-review

Abstract

Two novel assays, a restriction fragment length polymorphism (RFLP) assay and an assay based on the 5'-nuclease activity of Taq DNA polymerase, were developed for screening viral variants in lamivudine-treated patients' sera containing

Original languageEnglish
Pages (from-to)3338-3347
Number of pages10
JournalJournal of Clinical Microbiology
Volume37
Issue number10
Publication statusPublished - 1999

ASJC Scopus subject areas

  • Microbiology (medical)
  • Microbiology

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