Tumour necrosis factor family genes in a phenotype of COPD associated with emphysema

I. Ferrarotti; M. Zorzetto; M. Beccaria; L. S. Gilè; R. Porta; N. Ambrosino; P. F. Pignatti; I. Cerveri; E. Pozzi; M. Luisetti

Tumour necrosis factor family genes in a phenotype of COPD associated with emphysema

I. Ferrarotti, M. Zorzetto, M. Beccaria, L. S. Gilè, R. Porta, N. Ambrosino, P. F. Pignatti, I. Cerveri, E. Pozzi, M. Luisetti

Research output: Contribution to journal › Article › peer-review

Abstract

Genetic factors are believed to play a role in the individual susceptibility to chronic obstructive pulmonary disease (COPD). Tumour necrosis factor (TNF) family genes have been widely investigated but inconsistent results may lie either in the genetic heterogeneity of populations or in the poor phenotype definition. A genetic study was performed using a narrower phenotype of COPD. The authors studied 86 healthy smokers and 63 COPD subjects who were enrolled based on irreversible airflow obstruction (forced expiratory volume in one second/forced vital capacity

Original language	English
Pages (from-to)	444-449
Number of pages	6
Journal	European Respiratory Journal
Volume	21
Issue number	3
Publication status	Published - Mar 1 2003

Keywords

Association study
Candidate gene
Complex traits
Gene polymorphisms
Polymerase chain reaction

ASJC Scopus subject areas

Pulmonary and Respiratory Medicine

Cite this

@article{ffe26fdb1fe9427f9ee27fdd1ca8aeb2,

title = "Tumour necrosis factor family genes in a phenotype of COPD associated with emphysema",

abstract = "Genetic factors are believed to play a role in the individual susceptibility to chronic obstructive pulmonary disease (COPD). Tumour necrosis factor (TNF) family genes have been widely investigated but inconsistent results may lie either in the genetic heterogeneity of populations or in the poor phenotype definition. A genetic study was performed using a narrower phenotype of COPD. The authors studied 86 healthy smokers and 63 COPD subjects who were enrolled based on irreversible airflow obstruction (forced expiratory volume in one second/forced vital capacity ",

keywords = "Association study, Candidate gene, Complex traits, Gene polymorphisms, Polymerase chain reaction",

author = "I. Ferrarotti and M. Zorzetto and M. Beccaria and Gil{\`e}, {L. S.} and R. Porta and N. Ambrosino and Pignatti, {P. F.} and I. Cerveri and E. Pozzi and M. Luisetti",

year = "2003",

month = mar,

day = "1",

language = "English",

volume = "21",

pages = "444--449",

journal = "European Journal of Respiratory Diseases",

issn = "0903-1936",

publisher = "European Respiratory Society",

number = "3",

}

TY - JOUR

T1 - Tumour necrosis factor family genes in a phenotype of COPD associated with emphysema

AU - Ferrarotti, I.

AU - Zorzetto, M.

AU - Beccaria, M.

AU - Gilè, L. S.

AU - Porta, R.

AU - Ambrosino, N.

AU - Pignatti, P. F.

AU - Cerveri, I.

AU - Pozzi, E.

AU - Luisetti, M.

PY - 2003/3/1

Y1 - 2003/3/1

N2 - Genetic factors are believed to play a role in the individual susceptibility to chronic obstructive pulmonary disease (COPD). Tumour necrosis factor (TNF) family genes have been widely investigated but inconsistent results may lie either in the genetic heterogeneity of populations or in the poor phenotype definition. A genetic study was performed using a narrower phenotype of COPD. The authors studied 86 healthy smokers and 63 COPD subjects who were enrolled based on irreversible airflow obstruction (forced expiratory volume in one second/forced vital capacity

AB - Genetic factors are believed to play a role in the individual susceptibility to chronic obstructive pulmonary disease (COPD). Tumour necrosis factor (TNF) family genes have been widely investigated but inconsistent results may lie either in the genetic heterogeneity of populations or in the poor phenotype definition. A genetic study was performed using a narrower phenotype of COPD. The authors studied 86 healthy smokers and 63 COPD subjects who were enrolled based on irreversible airflow obstruction (forced expiratory volume in one second/forced vital capacity

KW - Association study

KW - Candidate gene

KW - Complex traits

KW - Gene polymorphisms

KW - Polymerase chain reaction

UR - http://www.scopus.com/inward/record.url?scp=0037345725&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0037345725&partnerID=8YFLogxK

M3 - Article

C2 - 12661999

AN - SCOPUS:0037345725

SN - 0903-1936

VL - 21

SP - 444

EP - 449

JO - European Journal of Respiratory Diseases

JF - European Journal of Respiratory Diseases

IS - 3

ER -

Tumour necrosis factor family genes in a phenotype of COPD associated with emphysema

Abstract

Keywords

ASJC Scopus subject areas

Other files and links

Fingerprint

Cite this