Tulip bundle technique and fibrin glue injection: Unusual treatment of colonic perforation

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We report a case of a 63-year-old male who experienced an iatrogenic sigmoid perforation repaired combining three endoscopic techniques. The lesion was large and irregular with three discrete perforations, therefore, we decided to close it by placing one clip per perforation, and then connecting all the clips with two endoloops. Finally we chose to use a fibrin glue injection to obtain a complete sealing. Four days after the colonoscopy the patient underwent a laparoscopic right hemicolectomy due to evidence of a large polyp of the caecum with high grade dysplasia and focal carcinoma in situ. Inspection of the sigma showed complete repair of the perforation. This report underlines how a conservative approach, together with a combination of various endoscopic techniques, can resolve complicated iatrogenic perforations of the colon.

Original languageEnglish
Pages (from-to)1088-1090
Number of pages3
JournalWorld Journal of Gastroenterology
Issue number8
Publication statusPublished - Feb 28 2011


  • Colonic perforation
  • Endoscopic treatment
  • Fibrin glue injection
  • Tulip bundle technique

ASJC Scopus subject areas

  • Gastroenterology


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