Tropisetron-dexamethasone combination for carboplatin-induced emesis

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Sixty-six patients being given polychemotherapy schedules including carboplatin entered an antiemetic protocol with tropisetron and dexamethasone at the dose of 5 mg and 8 mg respectively. A complete response (no episodes of vomiting) and a major response (≤2 episodes of vomiting) were observed in 55 and 7 patients respectively. It is concluded that the tropisetron-dexamethasone combination is highly active in the control of emesis induced by conventional doses of carboplatin in combination.

Original languageEnglish
Pages (from-to)1179-1181
Number of pages3
JournalOncology Reports
Issue number6
Publication statusPublished - 1996


  • carboplatin
  • dexamethasone
  • emesis
  • tropisetron

ASJC Scopus subject areas

  • Cancer Research
  • Oncology


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