TY - JOUR
T1 - Triton WR 1339
T2 - Effect on the reticulo-endothelial system (RES) activity in tumor-bearing mice
AU - Franchi, G.
AU - Innocenti, I. Reyers Degli
AU - Standen, S.
AU - Garattini, S.
PY - 1973
Y1 - 1973
N2 - The reticulo-endothelial system (RES) activity in normal and in intracerebral Sarcoma 180-bearing mice was investigated after acute or subchronic treatment with the non-ionic surface-active agent: Triton WR 1339 (TWR). While the single treatment is ineffective, the subchronic treatment markedly raises the phagocytic index not only in normal mice but also in tumor-bearing animals where the RES is depressed by the presence of disseminating cancer cells. A possible relation between the RES stimulatory capacity and the antimetastatic effect exerted by TWR is envisaged.
AB - The reticulo-endothelial system (RES) activity in normal and in intracerebral Sarcoma 180-bearing mice was investigated after acute or subchronic treatment with the non-ionic surface-active agent: Triton WR 1339 (TWR). While the single treatment is ineffective, the subchronic treatment markedly raises the phagocytic index not only in normal mice but also in tumor-bearing animals where the RES is depressed by the presence of disseminating cancer cells. A possible relation between the RES stimulatory capacity and the antimetastatic effect exerted by TWR is envisaged.
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U2 - 10.1016/0014-2964(73)90132-1
DO - 10.1016/0014-2964(73)90132-1
M3 - Article
C2 - 4803226
AN - SCOPUS:0015644879
SN - 0014-2964
VL - 9
SP - 487
EP - 490
JO - European Journal of Cancer
JF - European Journal of Cancer
IS - 7
ER -