Abstract
Five patients with neuropathy and IgM M-proteins that reacted with myelin-associated glycoprotein (MAG) were treated for 10 to 20 months with cytostatic agents. In 2 patients, a decrease in serum M-protein and in anti-MAG IgM levels coincided with a progressive improvement of neuropathy. No clinical improvement and no decrease of anti-MAG IgM were observed in the other patients. The close relationship between the decrease of anti-MAG M-proteins and clinical improvement in these patients supports the pathogenetic role of the M-protein in the neuropathy.
Original language | English |
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Pages (from-to) | 93-97 |
Number of pages | 5 |
Journal | Annals of Neurology |
Volume | 24 |
Issue number | 1 |
Publication status | Published - 1988 |
ASJC Scopus subject areas
- Neuroscience(all)