Treatment of elderly patients affected by lung cancer: Why to treat, when to treat and what we know

Alessandra Bearz, Massimiliano Berretta, Arben Lleshi, Eleonora Berto, Umberto Tirelli

Research output: Contribution to journalArticlepeer-review

Abstract

In the recent years many advances have been achieved in the field of the treatment of lung cancer, with the development of novel therapeutic pathways due to the knowledge of oncologic drivers involved in the carcinogenesis of the lung, as well as the involvement of new radiotherapic and surgical techniques. Nevertheless, the standard treatment for elderly is still debated, mainly because of an underrepresentation of elderly patients in clinical trials. Herein we try to summarize the main guidelines for the treatment of lung cancer, with particular attention for the elderly patients, what we know and what has changed.

Original languageEnglish
Pages (from-to)1378-1382
Number of pages5
JournalAnti-Cancer Agents in Medicinal Chemistry
Volume13
Issue number9
DOIs
Publication statusPublished - 2013

Keywords

  • Adjuvant treatment
  • Chemotherapy
  • Clinical trials
  • Comprehensive geriatric assessment
  • Cutoff point
  • Elderly patients
  • Geriatric oncology
  • Locally advanced nsclc
  • Lung cancer
  • Metastatic lung cancer
  • Multimodality treatment
  • Non-small cell lung cancer
  • Radiotherapy
  • Small cell lung cancer
  • Surgery

ASJC Scopus subject areas

  • Cancer Research
  • Molecular Medicine
  • Pharmacology
  • Medicine(all)

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