Treatment of Chronic Urticaria

Riccardo Asero, Alberto Tedeschi, Massimo Cugno

Research output: Contribution to journalArticlepeer-review


Second-generation antihistamines are unquestionably the first-line treatment for chronic urticaria and can be used at higher than licensed doses if normal doses fail to control the disease. A short course of oral corticosteroids should be considered for patients not responding to antihistamines before trying other immunosuppressive drugs. Ciclosporin is effective in most antihistamine-resistant patients who require long-term corticosteroid treatments to control their disease. Omalizumab is effective in most subsets of chronic urticaria sufferers who do not respond to other treatments but its high cost represents a limitation to its widespread use.

Original languageEnglish
Pages (from-to)105-116
Number of pages12
JournalImmunology and Allergy Clinics of North America
Issue number1
Publication statusPublished - Feb 2014


  • Antihistamines
  • Chronic urticaria
  • Ciclosporin
  • Corticosteroids
  • Omalizumab
  • Therapy

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology


Dive into the research topics of 'Treatment of Chronic Urticaria'. Together they form a unique fingerprint.

Cite this