Total laparoendoscopic single-site surgery (LESS) hysterectomy in low-risk early endometrial cancer: A pilot study

Francesco Fanfani, Cristiano Rossitto, Maria Lucia Gagliardi, Valerio Gallotta, Salvatore Gueli Alletti, Giovanni Scambia, Anna Fagotti

Research output: Contribution to journalArticlepeer-review


Background In the last few years, technical advances have produced a dramatic shift from traditional open surgery toward a minimally invasive approach, even in oncological procedures. We present our initial experience with laparoendoscopic single-site surgery (LESS) in the surgical treatment of early-stage endometrial cancer patients. Methods Between July 2009 and May 2010, 20 consecutive low-risk early endometrial cancer patients were enrolled in this single institution prospective cohort trial. Results The median age of the patients was 57 years (range = 42-68) and median body mass index was 24 kg/m 2 (range = 21-30). Median operative time was 105 min (range = 85-155) and median estimated blood loss was 20 ml (range = 10-180). The larger skin and fascial incision required for the single-port approach was 2.5 cm (median = 2.2 cm; range = 2.0-2.5). No laparoscopic/laparotomic conversion was registered, and no insertion of additional ports was necessary. Median ileus was 16 h (range = 12-20) and median time to discharge was 1 day (range = 1-2). All patients were completely satisfied with the cosmetic results and postoperative pain control. Conclusions Laparoendoscopic single-site surgery could represent a surgical option for extra-fascial hysterectomy in early-stage endometrial cancer patients, with the potential to further decrease invasiveness of the conventional laparoscopic approach.

Original languageEnglish
Pages (from-to)41-46
Number of pages6
JournalSurgical Endoscopy and Other Interventional Techniques
Issue number1
Publication statusPublished - Jan 2012


  • Early-stage endometrial cancer
  • Laparoendoscopic single-site surgery
  • Single port

ASJC Scopus subject areas

  • Surgery


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