Thrombophilia and fetal germinal matrix-intraventricular hemorrhage: Does it matter?

L. A. Ramenghi; M. Fumagalli; A. Righini; F. Triulzi; A. Kustermann; F. Mosca

doi:10.1002/uog.2586

Thrombophilia and fetal germinal matrix-intraventricular hemorrhage: Does it matter?

L. A. Ramenghi, M. Fumagalli, A. Righini, F. Triulzi, A. Kustermann, F. Mosca

Fondazione IRCCS Ca' Granda- Ospedale Maggiore Policlinico

Research output: Contribution to journal › Article › peer-review

Abstract

Germinal matrix-intraventricular hemorrhage (GMH-IVH) in the fetus is very rare and the role of thrombophilia in its pathogenesis is unclear. We report on the prenatal diagnosis by magnetic resonance imaging of GMH-IVH in a 24-week fetus. The newborn presented posthemorrhagic ventriculomegaly and was found to be heterozygous for two thrombophilic patterns, factor V Leiden and methylenetetrahydrofolate reductase mutation. The combination of this hypercoagulable state and prenatal GMH-IVH is discussed together with the opportunity of testing these infants for thrombophilia.

Original language	English
Pages (from-to)	574-576
Number of pages	3
Journal	Ultrasound in Obstetrics and Gynecology
Volume	26
Issue number	5
DOIs	https://doi.org/10.1002/uog.2586
Publication status	Published - Oct 2005

Keywords

Factor V leiden
Fetal hemorrhage
GMH-IVH
Thrombophilia

ASJC Scopus subject areas

Obstetrics and Gynaecology
Radiology Nuclear Medicine and imaging
Reproductive Medicine
Acoustics and Ultrasonics
Radiological and Ultrasound Technology

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10.1002/uog.2586

Cite this

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abstract = "Germinal matrix-intraventricular hemorrhage (GMH-IVH) in the fetus is very rare and the role of thrombophilia in its pathogenesis is unclear. We report on the prenatal diagnosis by magnetic resonance imaging of GMH-IVH in a 24-week fetus. The newborn presented posthemorrhagic ventriculomegaly and was found to be heterozygous for two thrombophilic patterns, factor V Leiden and methylenetetrahydrofolate reductase mutation. The combination of this hypercoagulable state and prenatal GMH-IVH is discussed together with the opportunity of testing these infants for thrombophilia.",

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T2 - Does it matter?

AU - Ramenghi, L. A.

AU - Fumagalli, M.

AU - Righini, A.

AU - Triulzi, F.

AU - Kustermann, A.

AU - Mosca, F.

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AB - Germinal matrix-intraventricular hemorrhage (GMH-IVH) in the fetus is very rare and the role of thrombophilia in its pathogenesis is unclear. We report on the prenatal diagnosis by magnetic resonance imaging of GMH-IVH in a 24-week fetus. The newborn presented posthemorrhagic ventriculomegaly and was found to be heterozygous for two thrombophilic patterns, factor V Leiden and methylenetetrahydrofolate reductase mutation. The combination of this hypercoagulable state and prenatal GMH-IVH is discussed together with the opportunity of testing these infants for thrombophilia.

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KW - Fetal hemorrhage

KW - GMH-IVH

KW - Thrombophilia

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Thrombophilia and fetal germinal matrix-intraventricular hemorrhage: Does it matter?

Abstract

Keywords

ASJC Scopus subject areas

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