TY - JOUR
T1 - Therapeutic benefits from nanoparticles
T2 - The potential significance of nanoscience in diseases with compromise to the blood brain barrier
AU - Krol, Silke
AU - Macrez, Richard
AU - Docagne, Fabian
AU - Defer, Gilles
AU - Laurent, Sophie
AU - Rahman, Masoud
AU - Hajipour, Mohammad J.
AU - Kehoe, Patrick G.
AU - Mahmoudi, Morteza
PY - 2013/3/13
Y1 - 2013/3/13
N2 - Nanotechnology is an area of growing public interest. Its attractiveness stems from the promise offered socially and economically by the recent significant advances in nanotechnological development. Nanotechnology has already begun to be incorporated into the daily lives, but the level of its technological impact has yet to become clear. As a result, new properties never previously observed in these materials in either bulk form or as part of larger scale entities can be harnessed. Chemical processes can be tailored to a desired application, such as the enhancement of biocompatibility of implantable materials, for example. Due to their greater surface area per volume, nanomaterials can exhibit higher reactivity, increased capacity for mechanical strength, or magnetic or electrical properties. Targeted molecular imaging is important for a wide range of diagnostic purposes, such as the identification of inflammatory loci, the localization and staging of tumors, the visualization of vascular structures or specific disease states, and the examination of anatomy.
AB - Nanotechnology is an area of growing public interest. Its attractiveness stems from the promise offered socially and economically by the recent significant advances in nanotechnological development. Nanotechnology has already begun to be incorporated into the daily lives, but the level of its technological impact has yet to become clear. As a result, new properties never previously observed in these materials in either bulk form or as part of larger scale entities can be harnessed. Chemical processes can be tailored to a desired application, such as the enhancement of biocompatibility of implantable materials, for example. Due to their greater surface area per volume, nanomaterials can exhibit higher reactivity, increased capacity for mechanical strength, or magnetic or electrical properties. Targeted molecular imaging is important for a wide range of diagnostic purposes, such as the identification of inflammatory loci, the localization and staging of tumors, the visualization of vascular structures or specific disease states, and the examination of anatomy.
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U2 - 10.1021/cr200472g
DO - 10.1021/cr200472g
M3 - Article
C2 - 23157552
AN - SCOPUS:84875154058
SN - 0009-2665
VL - 113
SP - 1877
EP - 1903
JO - Chemical Reviews
JF - Chemical Reviews
IS - 3
ER -