TY - JOUR
T1 - The role of rehabilitation in deep brain stimulation of the subthalamic nucleus for Parkinson's disease
T2 - A pilot study
AU - Tassorelli, Cristina
AU - Buscone, Simona
AU - Sandrini, Giorgio
AU - Pacchetti, Claudio
AU - Furnari, Anna
AU - Zangaglia, Roberta
AU - Bartolo, Michelangelo
AU - Nappi, Giuseppe
AU - Martignoni, Emilia
PY - 2009/11/5
Y1 - 2009/11/5
N2 - Bilateral deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an efficacious therapeutic option in the treatment of advanced Parkinson's disease (PD). The procedure may be however associated with functional impairment of different types and intensity. In this paper we describe the functional impairments detected in a group of 34 subjects with PD who were submitted to DBS. These patients belonged to a cohort of 75 consecutive PD patients who underwent the surgical procedure. The rehabilitation program included physiotherapy exercises for recovery/maintenance of the range of motion, active exercises, exercises for coordination and proprioception, and walking training based on the use of sensory cues, with daily sessions for a period of 4-8 weeks. The motor examination section of unified Parkinson's disease rating scale (UPDRS-ME) and the functional independence measure (FIM) scores showed a consistent and significant improvement in the patients' motor performances. The reported findings suggest that rehabilitation may play an important role in the correction of specific functional impairments caused by or associated with DBS in PD.
AB - Bilateral deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an efficacious therapeutic option in the treatment of advanced Parkinson's disease (PD). The procedure may be however associated with functional impairment of different types and intensity. In this paper we describe the functional impairments detected in a group of 34 subjects with PD who were submitted to DBS. These patients belonged to a cohort of 75 consecutive PD patients who underwent the surgical procedure. The rehabilitation program included physiotherapy exercises for recovery/maintenance of the range of motion, active exercises, exercises for coordination and proprioception, and walking training based on the use of sensory cues, with daily sessions for a period of 4-8 weeks. The motor examination section of unified Parkinson's disease rating scale (UPDRS-ME) and the functional independence measure (FIM) scores showed a consistent and significant improvement in the patients' motor performances. The reported findings suggest that rehabilitation may play an important role in the correction of specific functional impairments caused by or associated with DBS in PD.
KW - Deep brain stimulation
KW - Neurorehabilitation
KW - Parkinson's disease
KW - Physical therapy
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U2 - 10.1016/j.parkreldis.2009.03.006
DO - 10.1016/j.parkreldis.2009.03.006
M3 - Article
C2 - 19398215
AN - SCOPUS:70350270366
SN - 1353-8020
VL - 15
SP - 675
EP - 681
JO - Parkinsonism and Related Disorders
JF - Parkinsonism and Related Disorders
IS - 9
ER -