The role of micronutrients in the diet of HIV-1-infected individuals

Giuseppe Nunnari, Christian Coco, Marilia Rita Pinzone, Piero Pavone, Massimiliano Berretta, Michelino Di Rosa, Matthias Schnell, Giorgio Calabrese, Bruno Cacopardo

Research output: Contribution to journalArticlepeer-review


Vitamins, zinc and selenium are important micronutrients that play crucial functions at the cellular and molecular level. Immune response of several different cell types can be modulated by these micronutrients. Deficiency in micronutrients has been extensively reported in HIV-1-infected individuals and further correlated with CD4+ T-cell count, HIV-1 plasma viral load, disease progression and mortality. Supplementation by micronutrients has had controversial effects. Thorough future investigations and trials are certainly needed to strategically plan evidence-based interventions. Here, we review the available data on use of micronutrients during the course of HIV-1 infection.

Original languageEnglish
Pages (from-to)2442-2456
Number of pages15
JournalFrontiers in Bioscience - Elite
Volume4 E
Issue number7
Publication statusPublished - Jan 1 2012


  • Anti-oxidants
  • Diet
  • HIV
  • Review
  • Selenium
  • Vitamins
  • Zinc

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Microbiology(all)
  • Medicine(all)


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