Ruolo della deformabilità eritrocitaria sul prolungamento del tempo di emorragia nel paziente epatopatico.

M. Moia; D. Mari; M. P. Coccato; P. Della Valle; A. Tripodi; P. M. Mannucci

Ruolo della deformabilità eritrocitaria sul prolungamento del tempo di emorragia nel paziente epatopatico.

Translated title of the contribution: The role of erythrocyte deformability in the prolonged bleeding time in liver disease patients

M. Moia, D. Mari, M. P. Coccato, P. Della Valle, A. Tripodi, P. M. Mannucci

Research output: Contribution to journal › Article › peer-review

Abstract

Hematocrit (Ht), red cell deformability (RCD) determined using a filtration method and bleeding time (BT) have been studied in 28 patients with severe chronic liver disease. Our results show a decrease of Ht (p less than 0.001), RCD (p less than 0.05) and a prolongation of BT (p less than 0.001) not related to the platelet count. Moreover, inverse relationships between Ht and BT (r = -0.52; p less than 0.01) and between RCD and BT (r = -0.54; p less than 0.01) have been found. We conclude that hemorheological alterations, such as decreased Ht and RCD, play an important role in primary hemostasis of patients with chronic liver disease.

Translated title of the contribution	The role of erythrocyte deformability in the prolonged bleeding time in liver disease patients
Original language	Italian
Pages (from-to)	213-218
Number of pages	6
Journal	La Ricerca in Clinica e in Laboratorio
Volume	15 Suppl 1
Publication status	Published - 1985

ASJC Scopus subject areas

Clinical Biochemistry

Cite this

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title = "Ruolo della deformabilit{\`a} eritrocitaria sul prolungamento del tempo di emorragia nel paziente epatopatico.",

abstract = "Hematocrit (Ht), red cell deformability (RCD) determined using a filtration method and bleeding time (BT) have been studied in 28 patients with severe chronic liver disease. Our results show a decrease of Ht (p less than 0.001), RCD (p less than 0.05) and a prolongation of BT (p less than 0.001) not related to the platelet count. Moreover, inverse relationships between Ht and BT (r = -0.52; p less than 0.01) and between RCD and BT (r = -0.54; p less than 0.01) have been found. We conclude that hemorheological alterations, such as decreased Ht and RCD, play an important role in primary hemostasis of patients with chronic liver disease.",

author = "M. Moia and D. Mari and Coccato, {M. P.} and {Della Valle}, P. and A. Tripodi and Mannucci, {P. M.}",

year = "1985",

language = "Italian",

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TY - JOUR

T1 - Ruolo della deformabilità eritrocitaria sul prolungamento del tempo di emorragia nel paziente epatopatico.

AU - Moia, M.

AU - Mari, D.

AU - Coccato, M. P.

AU - Della Valle, P.

AU - Tripodi, A.

AU - Mannucci, P. M.

PY - 1985

Y1 - 1985

N2 - Hematocrit (Ht), red cell deformability (RCD) determined using a filtration method and bleeding time (BT) have been studied in 28 patients with severe chronic liver disease. Our results show a decrease of Ht (p less than 0.001), RCD (p less than 0.05) and a prolongation of BT (p less than 0.001) not related to the platelet count. Moreover, inverse relationships between Ht and BT (r = -0.52; p less than 0.01) and between RCD and BT (r = -0.54; p less than 0.01) have been found. We conclude that hemorheological alterations, such as decreased Ht and RCD, play an important role in primary hemostasis of patients with chronic liver disease.

AB - Hematocrit (Ht), red cell deformability (RCD) determined using a filtration method and bleeding time (BT) have been studied in 28 patients with severe chronic liver disease. Our results show a decrease of Ht (p less than 0.001), RCD (p less than 0.05) and a prolongation of BT (p less than 0.001) not related to the platelet count. Moreover, inverse relationships between Ht and BT (r = -0.52; p less than 0.01) and between RCD and BT (r = -0.54; p less than 0.01) have been found. We conclude that hemorheological alterations, such as decreased Ht and RCD, play an important role in primary hemostasis of patients with chronic liver disease.

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Ruolo della deformabilità eritrocitaria sul prolungamento del tempo di emorragia nel paziente epatopatico.

Abstract

ASJC Scopus subject areas

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