TY - JOUR
T1 - The relevance of symptom perception in the management of severe asthma in adolescents
AU - Licari, Amelia
AU - Castagnoli, Riccardo
AU - Votto, Martina
AU - Marseglia, Gianluigi
AU - Ciprandi, Giorgio
PY - 2021/7/1
Y1 - 2021/7/1
N2 - BACKGROUND: Severe asthma in adolescents is a demanding challenge that deserves adequate management, including thorough work-up and rigorous follow-up. METHODS: We evaluated a group of adolescents with severe asthma to investigate the change over time of clinical, functional, and biological parameters. RESULTS: Most of adolescents treated with standard therapy improved, but some did not achieve an optimal asthma control and FeNO values increased. CONCLUSIONS: Despite guidelines-based therapy and clinical-functional improvement, type 2 inflammation could be not completely controlled. Biologics option could be considered if biomarkers suggest potential asthma relapse.
AB - BACKGROUND: Severe asthma in adolescents is a demanding challenge that deserves adequate management, including thorough work-up and rigorous follow-up. METHODS: We evaluated a group of adolescents with severe asthma to investigate the change over time of clinical, functional, and biological parameters. RESULTS: Most of adolescents treated with standard therapy improved, but some did not achieve an optimal asthma control and FeNO values increased. CONCLUSIONS: Despite guidelines-based therapy and clinical-functional improvement, type 2 inflammation could be not completely controlled. Biologics option could be considered if biomarkers suggest potential asthma relapse.
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U2 - 10.1701/3638.36188
DO - 10.1701/3638.36188
M3 - Article
C2 - 34263880
AN - SCOPUS:85111730944
SN - 0034-1193
VL - 112
SP - 529
EP - 531
JO - Recenti Progressi in Medicina
JF - Recenti Progressi in Medicina
IS - 7
ER -