The minimum information required for reporting a molecular interaction experiment (MIMIx)

Sandra Orchard; Lukasz Salwinski; Samuel Kerrien; Luisa Montecchi-Palazzi; Matthias Oesterheld; Volker Stümpflen; Arnaud Ceol; Andrew Chatr-Aryamontri; John Armstrong; Peter Woollard; John J. Salama; Susan Moore; Jérôme Wojcik; Gary D. Bader; Marc Vidal; Michael E. Cusick; Mark Gerstein; Anne Claude Gavin; Giulio Superti-Furga; Jack Greenblatt; Joel Bader; Peter Uetz; Mike Tyers; Pierre Legrain; Stan Fields; Nicola Mulder; Michael Gilson; Michael Niepmann; Lyle Burgoon; Javier De Las Rivas; Carlos Prieto; Victoria M. Perreau; Chris Hogue; Hans Werner Mewes; Rolf Apweiler; Ioannis Xenarios; David Eisenberg; Gianni Cesareni; Henning Hermjakob

doi:10.1038/nbt1324

The minimum information required for reporting a molecular interaction experiment (MIMIx)

Sandra Orchard, Lukasz Salwinski, Samuel Kerrien, Luisa Montecchi-Palazzi, Matthias Oesterheld, Volker Stümpflen, Arnaud Ceol, Andrew Chatr-Aryamontri, John Armstrong, Peter Woollard, John J. Salama, Susan Moore, Jérôme Wojcik, Gary D. Bader, Marc Vidal, Michael E. Cusick, Mark Gerstein, Anne Claude Gavin, Giulio Superti-Furga, Jack GreenblattJoel Bader, Peter Uetz, Mike Tyers, Pierre Legrain, Stan Fields, Nicola Mulder, Michael Gilson, Michael Niepmann, Lyle Burgoon, Javier De Las Rivas, Carlos Prieto, Victoria M. Perreau, Chris Hogue, Hans Werner Mewes, Rolf Apweiler, Ioannis Xenarios, David Eisenberg, Gianni Cesareni, Henning Hermjakob

Fondazione Santa Lucia

Research output: Contribution to journal › Article › peer-review

Abstract

A wealth of molecular interaction data is available in the literature, ranging from large-scale datasets to a single interaction confirmed by several different techniques. These data are all too often reported either as free text or in tables of variable format, and are often missing key pieces of information essential for a full understanding of the experiment. Here we propose MIMIx, the minimum information required for reporting a molecular interaction experiment. Adherence to these reporting guidelines will result in publications of increased clarity and usefulness to the scientific community and will support the rapid, systematic capture of molecular interaction data in public databases, thereby improving access to valuable interaction data.

Original language	English
Pages (from-to)	894-898
Number of pages	5
Journal	Nature Biotechnology
Volume	25
Issue number	8
DOIs	https://doi.org/10.1038/nbt1324
Publication status	Published - Aug 2007

ASJC Scopus subject areas

Microbiology

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Orchard, S., Salwinski, L., Kerrien, S., Montecchi-Palazzi, L., Oesterheld, M., Stümpflen, V., Ceol, A., Chatr-Aryamontri, A., Armstrong, J., Woollard, P., Salama, J. J., Moore, S., Wojcik, J., Bader, G. D., Vidal, M., Cusick, M. E., Gerstein, M., Gavin, A. C., Superti-Furga, G., ... Hermjakob, H. (2007). The minimum information required for reporting a molecular interaction experiment (MIMIx). Nature Biotechnology, 25(8), 894-898. https://doi.org/10.1038/nbt1324

Orchard, S, Salwinski, L, Kerrien, S, Montecchi-Palazzi, L, Oesterheld, M, Stümpflen, V, Ceol, A, Chatr-Aryamontri, A, Armstrong, J, Woollard, P, Salama, JJ, Moore, S, Wojcik, J, Bader, GD, Vidal, M, Cusick, ME, Gerstein, M, Gavin, AC, Superti-Furga, G, Greenblatt, J, Bader, J, Uetz, P, Tyers, M, Legrain, P, Fields, S, Mulder, N, Gilson, M, Niepmann, M, Burgoon, L, Rivas, JDL, Prieto, C, Perreau, VM, Hogue, C, Mewes, HW, Apweiler, R, Xenarios, I, Eisenberg, D, Cesareni, G & Hermjakob, H 2007, 'The minimum information required for reporting a molecular interaction experiment (MIMIx)', Nature Biotechnology, vol. 25, no. 8, pp. 894-898. https://doi.org/10.1038/nbt1324

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abstract = "A wealth of molecular interaction data is available in the literature, ranging from large-scale datasets to a single interaction confirmed by several different techniques. These data are all too often reported either as free text or in tables of variable format, and are often missing key pieces of information essential for a full understanding of the experiment. Here we propose MIMIx, the minimum information required for reporting a molecular interaction experiment. Adherence to these reporting guidelines will result in publications of increased clarity and usefulness to the scientific community and will support the rapid, systematic capture of molecular interaction data in public databases, thereby improving access to valuable interaction data.",

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AU - Oesterheld, Matthias

AU - Stümpflen, Volker

AU - Ceol, Arnaud

AU - Chatr-Aryamontri, Andrew

AU - Armstrong, John

AU - Woollard, Peter

AU - Salama, John J.

AU - Moore, Susan

AU - Wojcik, Jérôme

AU - Bader, Gary D.

AU - Vidal, Marc

AU - Cusick, Michael E.

AU - Gerstein, Mark

AU - Gavin, Anne Claude

AU - Superti-Furga, Giulio

AU - Greenblatt, Jack

AU - Bader, Joel

AU - Uetz, Peter

AU - Tyers, Mike

AU - Legrain, Pierre

AU - Fields, Stan

AU - Mulder, Nicola

AU - Gilson, Michael

AU - Niepmann, Michael

AU - Burgoon, Lyle

AU - Rivas, Javier De Las

AU - Prieto, Carlos

AU - Perreau, Victoria M.

AU - Hogue, Chris

AU - Mewes, Hans Werner

AU - Apweiler, Rolf

AU - Xenarios, Ioannis

AU - Eisenberg, David

AU - Cesareni, Gianni

AU - Hermjakob, Henning

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The minimum information required for reporting a molecular interaction experiment (MIMIx)

Abstract

ASJC Scopus subject areas

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