The largest multicentre data collection on prepectoral breast reconstruction: The iBAG study

Jaume Masià, Marzia Salgarello, Leonardo Cattelani, Pier Camillo Parodi, Diego Ribuffo, Maria Giuseppina Onesti, Giorgio Berna, Simon J. Cawthorn, Fernando Bozza, Stefano Duodeci, Simon Harries, Maurizio Governa, Roberto A. Barmasse, Raghavan Vidya, Tapan Sircar, Harleen Deol, Tommaso Guzzetti, Fabrizio Meggiolaro, Mauro Schiavon, Rishikesh ParmeshwarDouglas Ferguson, Caroline Mortimer, Giorgio Manca, Dinesh Thekkinkattil, Rathinasabapathy Rathinaezhil, Pud Bhaskar, Nicola Roche, Alberto Rivarossa, Gonzalo De Castro Parga, Samuele Massarut, Susanna Polotto, Mattia Di Bartolomeo, Emanuele Rampino Cordaro, Sebastiano Mura, Liliana Barone Adesi, Giovanni Marruzzo, Francesco Dell'Antonia, Monia Maritan, Tania Saibene, Silvia Michieletto, Claudia Cecconi, Manuele Maino, Dayalan Clarke, Sara Mirandola, Lucia Morelli, Mario Biral, Roberto Baraziol, Chiara Zanin, Chiara Gregorelli

Research output: Contribution to journalArticlepeer-review


Background and Objectives: In the last years, prepectoral breast reconstruction has increased its popularity, becoming a standard reconstructive technique by preserving pectoralis major anatomy and functionality. Nevertheless, the lack of solid and extensive data negatively impacts on surgeons’ correct information about postoperative complication rates and proper patient selection. This study aims to collect the largest evidence on this procedure. Methods: A multicentre retrospective audit, promoted by the Barcelona Hospital, collected the experience of 30 centers on prepectoral breast reconstruction with Braxon ADM. The study had the scientific support of INPECS and IIB societies which provided the online database Clinapsis. Results: A total of 1450 procedures were retrospectively collected in a 6-year period. Mean age 52.4 years, BMI 23.9, follow-up 22.7 months. Reconstruction was carried out after a tumor in 77.1% of the cases, 20.1% had prophylactic surgery, 2.8% had revisions. Diabetes, smoke, and immunosuppression had an influence on complications occurrence, as well as implant weight. Capsular contracture was associated with postoperative radiotherapy, but the overall rate was low (2.1%). Complications led to implant loss in 6.5% of the cases. Conclusions: The international Braxon Audit Group multicentre data collection represents a milestone in the field of breast reconstruction, extensively improving the knowledge on this procedure.

Original languageEnglish
Pages (from-to)848-860
Number of pages13
JournalJournal of Surgical Oncology
Issue number5
Publication statusPublished - Oct 1 2020


  • acellular dermal matrix
  • braxon
  • breast reconstruction
  • prepectoral
  • radiotherapy

ASJC Scopus subject areas

  • Surgery
  • Oncology


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