The influence of smoking on von Willebrand factor is already manifest in healthy adolescent females: The Floren-teen (Florence Teenager) Study

D. Prisco, S. Fedi, T. Brunelli, L. Chiarugi, A. Lombardi, R. Gianni, E. Santoro, C. Cappelletti, G. Pepe, G. F. Gensini, R. Abbate

Research output: Contribution to journalArticlepeer-review

Abstract

The early onset of atherosclerosis and the involvement of physiological biochemical, and environmental factors in its pathogenesis is well documented. Few data are available on the role of risk factors related to hemostasis in the pathogenesis of atherosclerosis in the young and, in particular, little information is available on adolescent populations. In the Study of Preventive Medicine and Education Program (Floren-teen Study), von Willebrand factor, a risk factor for cardiovascular disorder, was studied, together with classical cardiovascular risk factors, in apparently healthy students from two high schools in Florence. Familial and personal history, physical examination, and cardiovascular risk factors were evaluated in 144 students (aged 17-19 years). Blood was withdrawn to assess von Willebrand factor (ELISA) and lipid parameters. Levels of von Willebrand factor were significantly higher (P

Original languageEnglish
Pages (from-to)150-154
Number of pages5
JournalInternational Journal of Clinical & Laboratory Research
Volume29
Issue number4
DOIs
Publication statusPublished - Dec 1999

Keywords

  • Adolescents
  • Atherosclerosis
  • Coagulation
  • Von Willebrand factor

ASJC Scopus subject areas

  • Clinical Biochemistry

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