TY - JOUR
T1 - The impact of probiotics and prebiotics on the immune system
AU - Klaenhammer, Todd R.
AU - Kleerebezem, Michiel
AU - Kopp, Matthias Volkmar
AU - Rescigno, Maria
PY - 2012/10
Y1 - 2012/10
N2 - Probiotics and prebiotics are increasingly being added to foodstuffs with claims of health benefits. Probiotics are live microorganisms that are thought to have beneficial effects on the host, whereas prebiotics are ingredients that stimulate the growth and/or function of beneficial intestinal microorganisms. But can these products directly modulate immune function and influence inflammatory diseases? Here, Nature Reviews Immunology asks four experts to discuss these issues and provide their thoughts on the future application of probiotics as a disease therapy.
AB - Probiotics and prebiotics are increasingly being added to foodstuffs with claims of health benefits. Probiotics are live microorganisms that are thought to have beneficial effects on the host, whereas prebiotics are ingredients that stimulate the growth and/or function of beneficial intestinal microorganisms. But can these products directly modulate immune function and influence inflammatory diseases? Here, Nature Reviews Immunology asks four experts to discuss these issues and provide their thoughts on the future application of probiotics as a disease therapy.
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U2 - 10.1038/nri3312
DO - 10.1038/nri3312
M3 - Article
C2 - 23007572
AN - SCOPUS:84866714806
SN - 1474-1733
VL - 12
SP - 728
EP - 734
JO - Nature Reviews Immunology
JF - Nature Reviews Immunology
IS - 10
ER -