TY - JOUR
T1 - The evaluation of right ventricular performance in different clinical models of heart failure
AU - Campana, Carlo
AU - Pasotti, Michele
AU - Monti, Lorenzo
AU - Revera, Miriam
AU - Serio, Alessandra
AU - Nespoli, Luisa
AU - Magrini, Giulia
AU - Scelsi, Laura
AU - Ghio, Stefano
AU - Tavazzi, Luigi
PY - 2004/11
Y1 - 2004/11
N2 - To evaluate the role of right ventricular function in different clinical models of heart failure. 22 patients with pulmonary hypertension (PH) in WHO class III and IV (group A) were evaluated by echocardiography, brain natriuretic peptide (BNP) measurements and right heart catheterization at baseline and after a mean follow-up of 15 ± 4 months. 63 patients with chronic heart failure of different etiology, NYHA class IIIb-IV, followed-up for 18 ± 3 months (group B), underwent echocardiography, BNP measurements, right heart catheterization at study entry and follow-up. In group A patients, among hemodynamic parameters consistent with severe PH, right atrial pressure significantly increased (from 6.7 ± 4.8 to 10 ± 6.5 mmHg, p <0.01); BNP showed a negative correlation with right ventricular ejection fraction (r 2 = 0.46). In group B, mean left and right ventricular (thermodilution) ejection fraction (RVEF) were 21 ± 7% and 18 ± 9%; BNP showed significant correlations with pulmonary wedge pressure (r = 0.48, p = 0.02) and right ventricular function indices (RVEF and tricuspidal annular plane systolic excursion). A multiparametric right ventricular evaluation is useful even if several diagnostic and prognostic variables which were investigated in this study are not likely to show the same prognostic role in right and biventricular models of heart failure.
AB - To evaluate the role of right ventricular function in different clinical models of heart failure. 22 patients with pulmonary hypertension (PH) in WHO class III and IV (group A) were evaluated by echocardiography, brain natriuretic peptide (BNP) measurements and right heart catheterization at baseline and after a mean follow-up of 15 ± 4 months. 63 patients with chronic heart failure of different etiology, NYHA class IIIb-IV, followed-up for 18 ± 3 months (group B), underwent echocardiography, BNP measurements, right heart catheterization at study entry and follow-up. In group A patients, among hemodynamic parameters consistent with severe PH, right atrial pressure significantly increased (from 6.7 ± 4.8 to 10 ± 6.5 mmHg, p <0.01); BNP showed a negative correlation with right ventricular ejection fraction (r 2 = 0.46). In group B, mean left and right ventricular (thermodilution) ejection fraction (RVEF) were 21 ± 7% and 18 ± 9%; BNP showed significant correlations with pulmonary wedge pressure (r = 0.48, p = 0.02) and right ventricular function indices (RVEF and tricuspidal annular plane systolic excursion). A multiparametric right ventricular evaluation is useful even if several diagnostic and prognostic variables which were investigated in this study are not likely to show the same prognostic role in right and biventricular models of heart failure.
KW - BNP
KW - End-stage heart failure
KW - Pulmonary hypertension
KW - Right ventricular function
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U2 - 10.1016/j.ehjsup.2004.09.012
DO - 10.1016/j.ehjsup.2004.09.012
M3 - Article
AN - SCOPUS:8644289475
SN - 1520-765X
VL - 6
JO - European Heart Journal, Supplement
JF - European Heart Journal, Supplement
IS - 6
ER -