Abstract
The increasing use of orthopedic implants and, in particular, of hip and knee joint replacements for young and active patients, has stimulated interest and concern regarding the chronic, long-term effects of the materials used. This review focuses on the current knowledge of the adverse biologic reactions to metal particles released from orthopaedic implants in vivo and in vitro. More specifically, the purpose of this article is to provide an overview of the current literature about the adverse effects of metal particles on bone cells and peri-implant bone.
| Original language | English |
|---|---|
| Pages (from-to) | 34-40 |
| Number of pages | 7 |
| Journal | Clinical Cases in Mineral and Bone Metabolism |
| Volume | 10 |
| Issue number | 1 |
| Publication status | Published - Jan 2013 |
Keywords
- Adverse effects
- Bone cells
- Metal ions
- Orthopaedic implants
- Osteolysis
ASJC Scopus subject areas
- Endocrinology, Diabetes and Metabolism
- Internal Medicine