The alliance of mesenchymal stem cells, bone, and diabetes

Nicola Napoli; Rocky Strollo; Angela Paladini; Silvia I. Briganti; Paolo Pozzilli; Sol Epstein

doi:10.1155/2014/690783

The alliance of mesenchymal stem cells, bone, and diabetes

Nicola Napoli, Rocky Strollo, Angela Paladini, Silvia I. Briganti, Paolo Pozzilli, Sol Epstein

IRCCS Ospedale San Raffaele

Research output: Contribution to journal › Article › peer-review

Abstract

Bone fragility has emerged as a new complication of diabetes. Several mechanisms in diabetes may influence bone homeostasis by impairing the action between osteoblasts, osteoclasts, and osteocytes and/or changing the structural properties of the bone tissue. Some of these mechanisms can potentially alter the fate of mesenchymal stem cells, the initial precursor of the osteoblast. In this review, we describe the main factors that impair bone health in diabetic patients and their clinical impact.

Original language	English
Article number	690783
Journal	International Journal of Endocrinology
Volume	2014
DOIs	https://doi.org/10.1155/2014/690783
Publication status	Published - 2014

ASJC Scopus subject areas

Endocrine and Autonomic Systems
Endocrinology
Endocrinology, Diabetes and Metabolism

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10.1155/2014/690783

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AU - Epstein, Sol

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The alliance of mesenchymal stem cells, bone, and diabetes

Abstract

ASJC Scopus subject areas

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