TY - JOUR
T1 - Temporo-parietal junction is involved in attribution of hostile intentionality in social interactions
T2 - An rTMS study
AU - Giardina, Angela
AU - Caltagirone, Carlo
AU - Oliveri, Massimiliano
PY - 2011/5/16
Y1 - 2011/5/16
N2 - The temporal-parietal junction (TPJ) is a brain area implicated in social cognition, attention, integrating body-related information and self-processing. We investigated involvement of both the left and the right TPJ in a complex social cognitive task that required attributing intentions to other people. Fourteen healthy subjects participated in experiments that involved simulating interactions with other people in everyday conflicting situations. The task was performed following application of inhibitory trains of repetitive transcranial magnetic stimulation (rTMS) to the right and the left TPJ and to a control occipital brain site. Results showed a different pattern of involvement for the left and the right TPJ in judgements related to social interactions. When rTMS was applied to the right TPJ, attribution of hostile intentionality to the other increased and the tendency to interpret others' behaviour in terms of non-hostile intentionality decreased. By contrast, rTMS of the left TPJ tended to produce the opposite pattern, that is, attribution of non-hostile intentionality.
AB - The temporal-parietal junction (TPJ) is a brain area implicated in social cognition, attention, integrating body-related information and self-processing. We investigated involvement of both the left and the right TPJ in a complex social cognitive task that required attributing intentions to other people. Fourteen healthy subjects participated in experiments that involved simulating interactions with other people in everyday conflicting situations. The task was performed following application of inhibitory trains of repetitive transcranial magnetic stimulation (rTMS) to the right and the left TPJ and to a control occipital brain site. Results showed a different pattern of involvement for the left and the right TPJ in judgements related to social interactions. When rTMS was applied to the right TPJ, attribution of hostile intentionality to the other increased and the tendency to interpret others' behaviour in terms of non-hostile intentionality decreased. By contrast, rTMS of the left TPJ tended to produce the opposite pattern, that is, attribution of non-hostile intentionality.
KW - Body self
KW - Cognitive self
KW - Embodiment
KW - RTMS
KW - Social cognition
KW - Temporo-parietal junction
UR - http://www.scopus.com/inward/record.url?scp=79955140583&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79955140583&partnerID=8YFLogxK
U2 - 10.1016/j.neulet.2011.03.059
DO - 10.1016/j.neulet.2011.03.059
M3 - Article
C2 - 21443927
AN - SCOPUS:79955140583
SN - 0304-3940
VL - 495
SP - 150
EP - 154
JO - Neuroscience Letters
JF - Neuroscience Letters
IS - 2
ER -