Systemic administration of ephedrine induces Fos protein expression in caudate putamen and subthalamic nucleus of rats

Fabio Blandini; Shirley Ann Joseph; Cristina Tassorelli

Systemic administration of ephedrine induces Fos protein expression in caudate putamen and subthalamic nucleus of rats

Fabio Blandini, Shirley Ann Joseph, Cristina Tassorelli

Fondazione "Istituto Neurologico Casimiro Mondino"

Research output: Contribution to journal › Article › peer-review

Abstract

Systemic administration of ephedrine, an anti-hypotensive agent with central effects, induced dramatic expression of Fos protein in the caudate putamen (CPu) and subthalamic nucleus (STN) of rats. This may be related to dopaminergic agonist properties that have been attributed to this compound, dopamine receptors being present in both CPu and STN. This finding seems to suggest that central effects of ephedrine might be mediated by changes in basal ganglia outflow.

Original language	English
Pages (from-to)	293-296
Number of pages	4
Journal	Functional Neurology
Volume	12
Issue number	5
Publication status	Published - Sept 1997

Keywords

Caudate putamen
Ephedrine
Fos
Subthalamic nucleus

ASJC Scopus subject areas

Clinical Neurology
Neuroscience(all)

Cite this

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abstract = "Systemic administration of ephedrine, an anti-hypotensive agent with central effects, induced dramatic expression of Fos protein in the caudate putamen (CPu) and subthalamic nucleus (STN) of rats. This may be related to dopaminergic agonist properties that have been attributed to this compound, dopamine receptors being present in both CPu and STN. This finding seems to suggest that central effects of ephedrine might be mediated by changes in basal ganglia outflow.",

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author = "Fabio Blandini and Joseph, {Shirley Ann} and Cristina Tassorelli",

year = "1997",

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AU - Blandini, Fabio

AU - Joseph, Shirley Ann

AU - Tassorelli, Cristina

PY - 1997/9

Y1 - 1997/9

N2 - Systemic administration of ephedrine, an anti-hypotensive agent with central effects, induced dramatic expression of Fos protein in the caudate putamen (CPu) and subthalamic nucleus (STN) of rats. This may be related to dopaminergic agonist properties that have been attributed to this compound, dopamine receptors being present in both CPu and STN. This finding seems to suggest that central effects of ephedrine might be mediated by changes in basal ganglia outflow.

AB - Systemic administration of ephedrine, an anti-hypotensive agent with central effects, induced dramatic expression of Fos protein in the caudate putamen (CPu) and subthalamic nucleus (STN) of rats. This may be related to dopaminergic agonist properties that have been attributed to this compound, dopamine receptors being present in both CPu and STN. This finding seems to suggest that central effects of ephedrine might be mediated by changes in basal ganglia outflow.

KW - Caudate putamen

KW - Ephedrine

KW - Fos

KW - Subthalamic nucleus

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JO - Functional Neurology

JF - Functional Neurology

IS - 5

ER -

Systemic administration of ephedrine induces Fos protein expression in caudate putamen and subthalamic nucleus of rats

Abstract

Keywords

ASJC Scopus subject areas

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