Sympathetic hyperactivity in patients with ulcerative colitis

Simona Maule, Giulia Pierangeli, Sabina Cevoli, Daniela Grimaldi, Paolo Gionchetti, Giovanni Barbara, Fernando Rizzello, Vincenzo Stanghellini, Roberto Corinaldesi, Massimo Campieri, Pietro Cortelli

Research output: Contribution to journalArticlepeer-review


Hypo and hyperactivity of the autonomic nervous system have been associated with chronic bowel inflammation diseases. We investigated the autonomic function in 11 patients with chronic ulcerative colitis (UC) and 17 healthy controls by means of cardiovascular autonomic tests and heart rate variability. Autonomic responses were normal in patients and controls. At rest, LF/HF ratios were significantly (P <0.05) higher in chronic UC patients (2.4 ± 1.6) compared to controls (1.2 ± 1.0). Our results suggest a higher sympathetic tone at rest in patients with chronic UC.

Original languageEnglish
Pages (from-to)217-220
Number of pages4
JournalClinical Autonomic Research
Issue number4
Publication statusPublished - Jun 2007


  • Autonomic nervous system
  • Heart rate variability
  • Power spectrum analysis
  • Sympathetic nervous system
  • Ulcerative colitis

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)


Dive into the research topics of 'Sympathetic hyperactivity in patients with ulcerative colitis'. Together they form a unique fingerprint.

Cite this