Terapia chirurgica dell'ipertensione polmonare cronica tromboembolica mediante endoarteriectomia polmonare

Translated title of the contribution: Surgical treatment of chronic thromboembolic pulmonary hypertension with pulmonary endarterectomy

Andrea Maria D'Armini, Giorgio Zanotti, Matteo Pozzi, Salvatore Nicolardi, Corrado Tramontin, Vito G. Ruggieri, Marco Morsolini, Fabrizio Tancredi, Cristian Monterosso, Mario Viganò, M. Maurelli, T. Bianchi, R. Veronesi, M. Toscani, C. Dezza, M. A. Villani, M. Fuardo, M. Sottosanti, A. Braschi, V. EmmiG. Rodi, G. Sala Gallini, F. Capra Marzani, L. Tavazzi, C. Falcone, C. Campana, S. Ghio, A. Raisaro, L. Scelsi, C. Raineri, G. Magrini, C. Aprile, B. Greco, R. Dore, R. Passera, P. Quaretti, A. Azzaretti, G. Rodolico, C. Massa Saluzzo, V. Vespro, A. Valentini, E. Pozzi, I. Cerveri, M. C. Zoia, A. Corsico, C. Montecucco, R. Caporali, O. Epis, F. Piovella, M. Barone, E. Arbustini, M. Grasso, E. Dalla Toffola, L. Petrucci, E. Carlisi, C. Fracchia, G. Callegari, C. Klersy

Research output: Contribution to journalArticlepeer-review


Acute pulmonary embolism is the third most common cardiovascular disease in Italy with approximately 65 000 new cases a year. Appropriate medical therapy does not necessarily prevent evolution of acute pulmonary embolism into chronic thromboembolic pulmonary hypertension (CTEPH), which occurs in 0.1-4.0% of cases. In our country, there are approximately up to 2600 new CTEPH patients a year. CTEPH is a progressive and potentially lethal disease. Medical therapy is palliative and only surgery can modify its natural history. Pulmonary endarterectomy (PEA) is the treatment of choice and lung transplantation should be considered only when PEA is contraindicated. Currently, nearly 4000 PEAS have been performed worldwide. Approximately ten centers are able to carry out this intervention with excellent and permanent results. Solid experience and close multidisciplinary collaboration allow appropriate patient selection, rigorous surgical technique, and adequate postoperative management. All these aspects represent the key to the success in the treatment of CTEPH. After PEA, quality and expected length of life are similar to the age-matched general population and the only therapy required is oral anticoagulation.

Translated title of the contributionSurgical treatment of chronic thromboembolic pulmonary hypertension with pulmonary endarterectomy
Original languageItalian
Pages (from-to)454-463
Number of pages10
JournalGiornale Italiano di Cardiologia
Issue number7
Publication statusPublished - Jul 2006

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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