Sun exposure and melanoma prognostic factors

Maurizio Montella, Fabrizio Ayala, Lucia Benedetto, M. T. Corradin, Vincenzo De Giorgi, Guido Zannetti, G. Giudice, R. Forcignanò, K. Peris, Giusto Trevisan, Francesco Spagnolo, Paolo Antonio Ascierto

Research output: Contribution to journalArticlepeer-review


Previous studies have reported an association between sun exposure and the increased survival of patients with cutaneous melanoma (CM). The present study analyzed the association between ultraviolet (UV) light exposure and various prognostic factors in the Italian Clinical National Melanoma Registry. Clinical and sociodemographic features were collected, as well as information concerning sunbed exposure and holidays with sun exposure. Analyses were performed to investigate the association between exposure to UV and melanoma prognostic factors. Between December 2010 and December 2013, information was obtained on 2,738 melanoma patients from 38 geographically representative Italian sites. A total of 49% of the patients were >55 years old, 51% were men, 50% lived in the north of Italy and 57% possessed a high level of education (at least high school). A total of 8 patients had a family history of melanoma and 56% had a fair phenotype (Fitzpatrick skin type I or II). Of the total patients, 29% had been diagnosed with melanoma by a dermatologist; 29% of patients presented with a very thick melanoma (Breslow thickness, >2 mm) and 25% with an ulcerated melanoma. In total, 1% of patients had distant metastases and 13% exhibited lymph node involvement. Holidays with sun exposure 5 years prior to CM diagnosis were significantly associated with positive prognostic factors, including lower Breslow thickness (P

Original languageEnglish
Pages (from-to)2706-2714
Number of pages9
JournalOncology Letters
Issue number4
Publication statusPublished - Apr 1 2016


  • Breslow thickness
  • Melanoma
  • Prognosis
  • Sun exposure
  • Sunbed
  • Ulceration

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


Dive into the research topics of 'Sun exposure and melanoma prognostic factors'. Together they form a unique fingerprint.

Cite this