Substitutions at codon 22 of Alzheimer's Aβ peptide induce diverse conformational changes and apoptotic effects human cerebral endothelial cells

Medicine & Life Sciences

• Codon 85%
• Endothelial Cells 64%
• Serum Amyloid A Protein 57%
• Peptides 55%
• Amyloidosis, Cerebroarterial, App-Related 40%
• Cerebral Amyloid Angiopathy 30%
• Propidium 25%
• Cerebral Hemorrhage 23%
• Point Mutation 21%
• Amyloid 20%
• Alzheimer Disease 16%
• Flow Cytometry 16%
• Cell Culture Techniques 16%
• Amino Acids 15%
• Stroke 14%
• Staining and Labeling 14%
• Apoptosis 13%
• Phenotype 13%
• Mutation 12%
• Genes 8%

Chemical Compounds

• Apoptotic 100%
• Substitution Reaction 54%
• Peptide 50%
• Mutation 36%
• Propidium Iodide 29%
• Cytometry 22%
• Secondary Structure 19%
• Flow 13%
• Protein 8%
• Time 7%
• Acid 7%