TY - JOUR
T1 - Suboptimal use of neoadjuvant chemotherapy in radical cystectomy patients
T2 - A population-based study
AU - Schiffmann, Jonas
AU - Sun, Maxine
AU - Gandaglia, Giorgio
AU - Tian, Zhe
AU - Popa, Ioana
AU - Larcher, Alessandro
AU - Meskawi, Malek
AU - Briganti, Alberto
AU - McCormack, Michael
AU - Shariat, Shahrokh F.
AU - Montorsi, Francesco
AU - Graefen, Markus
AU - Saad, Fred
AU - Karakiewicz, Pierre I.
PY - 2016/3/1
Y1 - 2016/3/1
N2 - Introduction: We aimed to assess contemporary rates of neoadjuvant chemotherapy (NC) use. Methods: We relied on the Surveillance, Epidemiology and End Results (SEER)-Medicare database for non-metastatic, muscle-invasive (T2-T4a) urothelial carcinoma of the urinary bladder (UCUB) patients who underwent radical cystectomy (RC) between 1991 and 2009. Multivariable logistic regression analyses tested predictors of NC use, such as: T-stage, N-stage, year of diagnosis, age at diagnosis, gender, race, use of radiotherapy (RT), marital status, urban status, socioeconomic status, tumour grade, and Charlson comorbidity index (CCI). Results: Overall, 5207 patients treated with RC were identified. Of those, 332 (6.4%) received NC. The rate of NC increased over time from 6.1% (1991) to 15.0% (2009) (p
AB - Introduction: We aimed to assess contemporary rates of neoadjuvant chemotherapy (NC) use. Methods: We relied on the Surveillance, Epidemiology and End Results (SEER)-Medicare database for non-metastatic, muscle-invasive (T2-T4a) urothelial carcinoma of the urinary bladder (UCUB) patients who underwent radical cystectomy (RC) between 1991 and 2009. Multivariable logistic regression analyses tested predictors of NC use, such as: T-stage, N-stage, year of diagnosis, age at diagnosis, gender, race, use of radiotherapy (RT), marital status, urban status, socioeconomic status, tumour grade, and Charlson comorbidity index (CCI). Results: Overall, 5207 patients treated with RC were identified. Of those, 332 (6.4%) received NC. The rate of NC increased over time from 6.1% (1991) to 15.0% (2009) (p
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U2 - 10.5489/cuaj.3292
DO - 10.5489/cuaj.3292
M3 - Article
AN - SCOPUS:84960807777
SN - 1920-1214
VL - 10
SP - E82-E86
JO - Canadian Urological Association Journal
JF - Canadian Urological Association Journal
IS - 3-4
ER -