Study of bioassayable somatomedin on renal artery and vein

F. Minuto; A. Barreca; P. Grimaldi; R. Cocco; G. Garibotto; S. Ferrini; G. Giordano

doi:10.1007/BF03350423

Study of bioassayable somatomedin on renal artery and vein

F. Minuto, A. Barreca, P. Grimaldi, R. Cocco, G. Garibotto, S. Ferrini, G. Giordano

A.O.U. San Martino - IST, Istituto Nazionale Ricerca sul Cancro (GENOVA)

Research output: Contribution to journal › Article › peer-review

Abstract

Somatomedin was measured by rat bioassay in samples obtained from renal artery and vein, in order to study the role of this organ in the production of somatomedin activity. The results showed a significant difference, with an increase of the activity in the venous samples. According to the data reported in the literature with bioassay (low values) and radioreceptor assay (normal or high values) in nephropathic subjects, our results seem to suggest that the kidney mainly inactivates a specific somatomedin inhibitor.

Original language	English
Pages (from-to)	305-306
Number of pages	2
Journal	Journal of Endocrinological Investigation
Volume	2
Issue number	3
DOIs	https://doi.org/10.1007/BF03350423
Publication status	Published - 1979

Keywords

growth
renal insufficiency
somatomedin bioassay
Somatomedin biosynthesis
somatomedin inhibitor
somatomedin radioreceptorassay

ASJC Scopus subject areas

Endocrinology
Endocrinology, Diabetes and Metabolism

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10.1007/BF03350423

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abstract = "Somatomedin was measured by rat bioassay in samples obtained from renal artery and vein, in order to study the role of this organ in the production of somatomedin activity. The results showed a significant difference, with an increase of the activity in the venous samples. According to the data reported in the literature with bioassay (low values) and radioreceptor assay (normal or high values) in nephropathic subjects, our results seem to suggest that the kidney mainly inactivates a specific somatomedin inhibitor.",

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author = "F. Minuto and A. Barreca and P. Grimaldi and R. Cocco and G. Garibotto and S. Ferrini and G. Giordano",

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AU - Minuto, F.

AU - Barreca, A.

AU - Grimaldi, P.

AU - Cocco, R.

AU - Garibotto, G.

AU - Ferrini, S.

AU - Giordano, G.

PY - 1979

Y1 - 1979

N2 - Somatomedin was measured by rat bioassay in samples obtained from renal artery and vein, in order to study the role of this organ in the production of somatomedin activity. The results showed a significant difference, with an increase of the activity in the venous samples. According to the data reported in the literature with bioassay (low values) and radioreceptor assay (normal or high values) in nephropathic subjects, our results seem to suggest that the kidney mainly inactivates a specific somatomedin inhibitor.

AB - Somatomedin was measured by rat bioassay in samples obtained from renal artery and vein, in order to study the role of this organ in the production of somatomedin activity. The results showed a significant difference, with an increase of the activity in the venous samples. According to the data reported in the literature with bioassay (low values) and radioreceptor assay (normal or high values) in nephropathic subjects, our results seem to suggest that the kidney mainly inactivates a specific somatomedin inhibitor.

KW - growth

KW - renal insufficiency

KW - somatomedin bioassay

KW - Somatomedin biosynthesis

KW - somatomedin inhibitor

KW - somatomedin radioreceptorassay

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Study of bioassayable somatomedin on renal artery and vein

Abstract

Keywords

ASJC Scopus subject areas

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