Study of autoantibodies and the relationship between anticardiolipin antibodies and lupus anticoagulant in female patients with pregnancy-induced arterial hypertension

The aim of this study was to evaluate the relationship between anticardiolipin antibodies and lupus anticoagulant, and the prevalence of autoantibodies in a group of 48 hypertensive third trimester pregnant women. There was no correlation between levels of anticardiolipin and tests of lupus anticoagulant activity. Prevalence of autoantibodies was low, and the presence of anticardiolipin antibodies was not a marker for severe hypertension, trisymptomatic gestosis, or intrauterine growth retardation. In conclusion, our study did not reveal the presence of antiphospholipid antibodies in hypertensive third trimester pregnant women, but the results failed to show any concordance between anticardiolipin antibodies and lupus anticoagulant activity.