Striking improvement in a case of reduced ejection fraction heart failure with baroreflex activation therapy

Edoardo Gronda; Gianmaria Brambilla; Eric G. Lovett; Giuseppe Costantino; Dimitrios Georgakpoulos; Emilio Vanoli

doi:10.1016/j.jccase.2014.02.007

Striking improvement in a case of reduced ejection fraction heart failure with baroreflex activation therapy

Edoardo Gronda, Gianmaria Brambilla, Eric G. Lovett, Giuseppe Costantino, Dimitrios Georgakpoulos, Emilio Vanoli

IRCCS Multimedica

Research output: Contribution to journal › Article › peer-review

Abstract

A patient experiencing chronic New York Heart Association (NYHA) Class III heart failure with reduced left ventricular ejection fraction and signs of right ventricular dysfunction is treated with baroreflex activation therapy (BAT). Despite optimal medical therapy, the patient had repeatedly decompensated and was approaching a refractory terminal stage. BAT chronically reduced muscle sympathetic nerve activity and dramatically improved clinical presentation of the patient to NYHA Class I through 12 months of therapy. BAT may hold promise for patients with advanced heart failure and reduced ejection fraction who have exhausted conventional therapy options..

Original language	English
Pages (from-to)	4-6
Number of pages	3
Journal	Journal of Cardiology Cases
Volume	10
Issue number	1
DOIs	https://doi.org/10.1016/j.jccase.2014.02.007
Publication status	Published - 2014

Keywords

Autonomic nervous system
Baroreflex
Heart failure
Non-pharmacologic therapy

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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10.1016/j.jccase.2014.02.007

Cite this

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title = "Striking improvement in a case of reduced ejection fraction heart failure with baroreflex activation therapy",

abstract = "A patient experiencing chronic New York Heart Association (NYHA) Class III heart failure with reduced left ventricular ejection fraction and signs of right ventricular dysfunction is treated with baroreflex activation therapy (BAT). Despite optimal medical therapy, the patient had repeatedly decompensated and was approaching a refractory terminal stage. BAT chronically reduced muscle sympathetic nerve activity and dramatically improved clinical presentation of the patient to NYHA Class I through 12 months of therapy. BAT may hold promise for patients with advanced heart failure and reduced ejection fraction who have exhausted conventional therapy options..",

keywords = "Autonomic nervous system, Baroreflex, Heart failure, Non-pharmacologic therapy",

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AU - Lovett, Eric G.

AU - Costantino, Giuseppe

AU - Georgakpoulos, Dimitrios

AU - Vanoli, Emilio

PY - 2014

Y1 - 2014

N2 - A patient experiencing chronic New York Heart Association (NYHA) Class III heart failure with reduced left ventricular ejection fraction and signs of right ventricular dysfunction is treated with baroreflex activation therapy (BAT). Despite optimal medical therapy, the patient had repeatedly decompensated and was approaching a refractory terminal stage. BAT chronically reduced muscle sympathetic nerve activity and dramatically improved clinical presentation of the patient to NYHA Class I through 12 months of therapy. BAT may hold promise for patients with advanced heart failure and reduced ejection fraction who have exhausted conventional therapy options..

AB - A patient experiencing chronic New York Heart Association (NYHA) Class III heart failure with reduced left ventricular ejection fraction and signs of right ventricular dysfunction is treated with baroreflex activation therapy (BAT). Despite optimal medical therapy, the patient had repeatedly decompensated and was approaching a refractory terminal stage. BAT chronically reduced muscle sympathetic nerve activity and dramatically improved clinical presentation of the patient to NYHA Class I through 12 months of therapy. BAT may hold promise for patients with advanced heart failure and reduced ejection fraction who have exhausted conventional therapy options..

KW - Autonomic nervous system

KW - Baroreflex

KW - Heart failure

KW - Non-pharmacologic therapy

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Striking improvement in a case of reduced ejection fraction heart failure with baroreflex activation therapy

Abstract

Keywords

ASJC Scopus subject areas

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