Stages of early acute renal dysfunction in liver transplantation: The influence of graft function

I. Umbro; M. Rossi; F. Tinti; F. Fiacco; P. Piselli; S. Ianni; S. Ginanni Corradini; L. Poli; P. B. Berloco; A. P. Mitterhofer

doi:10.1016/j.transproceed.2012.06.020

Stages of early acute renal dysfunction in liver transplantation: The influence of graft function

I. Umbro, M. Rossi, F. Tinti, F. Fiacco, P. Piselli, S. Ianni, S. Ginanni Corradini, L. Poli, P. B. Berloco, A. P. Mitterhofer

Istituto Nazionale per le Malattie Infettive Lazzaro Spallanzani

Research output: Contribution to journal › Article › peer-review

Abstract

The development of early acute renal dysfunction (eARD) occurring in the first week after orthotopic liver transplantation (OLT) is mainly influenced by more severe degrees of pre-OLT hepatic insufficiency and liver graft dysfunction. The aim of our study was to evaluate the incidence of eARD post-OLT as well as its association with pre- and post-OLT hepatic dysfunction. We selected 54 end-stage liver disease patients who underwent OLT from 2008 to 2011. The prevalence of eARD was 53.7% (29/54) classified according to AKIN criteria in ARD-Risk (55.2%), ARD-Injury (27.6%) and ARD-Failure (17.2%). The worst stage of post-OLT eARD (eARD-Failure) seems to be influenced by the poor pre-OLT hepatic function as well as by early suboptimal recovery of graft function.

Original language	English
Pages (from-to)	1953-1955
Number of pages	3
Journal	Transplantation Proceedings
Volume	44
Issue number	7
DOIs	https://doi.org/10.1016/j.transproceed.2012.06.020
Publication status	Published - Sept 2012

ASJC Scopus subject areas

Surgery
Transplantation

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10.1016/j.transproceed.2012.06.020

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title = "Stages of early acute renal dysfunction in liver transplantation: The influence of graft function",

abstract = "The development of early acute renal dysfunction (eARD) occurring in the first week after orthotopic liver transplantation (OLT) is mainly influenced by more severe degrees of pre-OLT hepatic insufficiency and liver graft dysfunction. The aim of our study was to evaluate the incidence of eARD post-OLT as well as its association with pre- and post-OLT hepatic dysfunction. We selected 54 end-stage liver disease patients who underwent OLT from 2008 to 2011. The prevalence of eARD was 53.7% (29/54) classified according to AKIN criteria in ARD-Risk (55.2%), ARD-Injury (27.6%) and ARD-Failure (17.2%). The worst stage of post-OLT eARD (eARD-Failure) seems to be influenced by the poor pre-OLT hepatic function as well as by early suboptimal recovery of graft function.",

author = "I. Umbro and M. Rossi and F. Tinti and F. Fiacco and P. Piselli and S. Ianni and {Ginanni Corradini}, S. and L. Poli and Berloco, {P. B.} and Mitterhofer, {A. P.}",

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T2 - The influence of graft function

AU - Umbro, I.

AU - Rossi, M.

AU - Tinti, F.

AU - Fiacco, F.

AU - Piselli, P.

AU - Ianni, S.

AU - Ginanni Corradini, S.

AU - Poli, L.

AU - Berloco, P. B.

AU - Mitterhofer, A. P.

PY - 2012/9

Y1 - 2012/9

N2 - The development of early acute renal dysfunction (eARD) occurring in the first week after orthotopic liver transplantation (OLT) is mainly influenced by more severe degrees of pre-OLT hepatic insufficiency and liver graft dysfunction. The aim of our study was to evaluate the incidence of eARD post-OLT as well as its association with pre- and post-OLT hepatic dysfunction. We selected 54 end-stage liver disease patients who underwent OLT from 2008 to 2011. The prevalence of eARD was 53.7% (29/54) classified according to AKIN criteria in ARD-Risk (55.2%), ARD-Injury (27.6%) and ARD-Failure (17.2%). The worst stage of post-OLT eARD (eARD-Failure) seems to be influenced by the poor pre-OLT hepatic function as well as by early suboptimal recovery of graft function.

AB - The development of early acute renal dysfunction (eARD) occurring in the first week after orthotopic liver transplantation (OLT) is mainly influenced by more severe degrees of pre-OLT hepatic insufficiency and liver graft dysfunction. The aim of our study was to evaluate the incidence of eARD post-OLT as well as its association with pre- and post-OLT hepatic dysfunction. We selected 54 end-stage liver disease patients who underwent OLT from 2008 to 2011. The prevalence of eARD was 53.7% (29/54) classified according to AKIN criteria in ARD-Risk (55.2%), ARD-Injury (27.6%) and ARD-Failure (17.2%). The worst stage of post-OLT eARD (eARD-Failure) seems to be influenced by the poor pre-OLT hepatic function as well as by early suboptimal recovery of graft function.

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JO - Transplantation Proceedings

JF - Transplantation Proceedings

IS - 7

ER -

Stages of early acute renal dysfunction in liver transplantation: The influence of graft function

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ASJC Scopus subject areas

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