Spontaneous acute coronary dissection after cocaine abuse in a young woman

Federico Bizzarri, Sergio Mondillo, Francesco Guerrini, Riccardo Barbati, Giacomo Frati, Giuseppe Davoli

Research output: Contribution to journalArticlepeer-review


Spontaneous coronary artery dissection is an unusual trigger for acute coronary syndrome or sudden death, occurring more frequently in relatively young people and mainly in the female sex. The underlying mechanism is not completely understood, but predisposing factors may include metabolism and collagen synthesis disorders. The case of a 34-year-old woman who underwent coronary angiography for acute anterolateral myocardial ischemia after cocaine abuse is reported. Dissection of the left main trunk extending to both proximal descending anterior and circumflex arteries was detected and the patient was promptly and successfully managed with tirofiban hydrochloride infusion and urgent coronary artery bypass grafting.

Original languageEnglish
Pages (from-to)297-299
Number of pages3
JournalCanadian Journal of Cardiology
Issue number3
Publication statusPublished - Mar 1 2003


  • Bypass
  • Cocaine
  • Coronary disease

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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