Soft tissue augmentation applying a collagenated porcine dermal matrix during second stage surgery: A prospective multicenter case series

Kai R. Fischer, Tiziano Testori, Hannes Wachtel, Sven Mühlemann, Arndt Happe, Massimo Del Fabbro

Research output: Contribution to journalArticlepeer-review


Background: The achievement and preservation of an adequate amount of soft tissue around implants is a critical factor for the prognosis of the treatment. Purpose: To evaluate the effectiveness of a porcine dermal matrix applied during second stage implant surgery for horizontal soft tissue augmentation and preservation of dimensional stability. Materials and Methods: Twenty patients (mean age 50.2 ± 11.9 [SD] years) candidate to implant therapy and requiring soft tissue augmentation were recruited in four centers. Augmentation was performed in 24 cases. A porcine dermal matrix was placed into a buccal split-thickness pouch during uncovering surgery. Silicone impressions were taken before surgery (T0), 2 weeks later at suture removal (T2), 6 months (T3), and 24 months (T4) post augmentation. Dimensional changes of soft tissue were evaluated using superimposition of digitalized study casts. Results: Nineteen patients (23 implants) could be evaluated at 6 months and 13 patients (17 implants) at 24 months. After 6-month follow-up, there was a significant dimensional gain respect to baseline, averaging 0.83 ± 0.64 mm (P <.01). This did not change significantly at 24 months (0.77 ± 0.65 mm, P =.19). The gain was >0.5 mm in 65.2% and 64.7% of the cases, respectively. Soft tissue shrinkage averaged 34.2% ± 77.0% from T2 to T3 (P <.01) and did not change thereafter (P =.39). Shrinkage was more consistent in the posterior mandible than in the maxilla, but not significantly (P =.23 at 6-month and.36 at 24-month). No adverse events occurred. Conclusion: Within the limitations of this prospective case series, the use of a porcine dermal matrix may provide consistent soft tissue augmentation that maintains up to 24-month follow-up, although graft shrinkage may occur in the first 6 months, depending on the location of surgery.

Original languageEnglish
Pages (from-to)923-930
Number of pages8
JournalClinical Implant Dentistry and Related Research
Issue number5
Publication statusPublished - Oct 1 2019


  • acellular dermal matrix
  • dental implant
  • gingival thickness
  • second stage surgery
  • soft tissue augmentation

ASJC Scopus subject areas

  • Oral Surgery
  • Dentistry(all)


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