TY - JOUR
T1 - Socioeconomic characteristics, life style, diabetes, family history of cancer and risk of pancreatic cancer
AU - Sciallero, Stefania
AU - Bonelli, Luigina
AU - Saccomanno, Sebastiano
AU - Conio, Massimo
AU - Bruzzi, Paolo
AU - Pugliese, Vittorio
PY - 1993
Y1 - 1993
N2 - Objective: To investigate the relationship between socioeconomic characteristics, life style (coffee, alcohol and tobacco consumption), diabetes mellitus, first-degree family history of cancer and risk of exocrine pancreatic cancer. Design: Hospital-based case-control study. Methods: One hundred and fifty patients with exocrine panceatic cancer and 160 hospital controls were interviewed by trained personnel when still in hospital. Results: A statistically significant trend of increased risk of exocrine pancreatic cancer with a higher level of education was observed [relative risk (RR) = 1.55, confidence interval (Q) 1.10–2.19]. No association with other social characteristics (marital status, occupation and place of residence) and coffee, alcohol and tobacco consumption was found. There was a significantly increased risk of exocrine pancreatic cancer as the weekly consumption of spirits increased (RR = 1.52, Cl 1.06–2.19). Diabetes was associated with an increased risk of exocrine pancreatic cancer only when diagnosed less than 1 year prior to the interview (RR = 8.14, Cl 2.19–30.4). Conclusions: Our study confirms that there is an increased risk of exocrine pancreatic cancer associated with alcohol consumption. In addition, we observed a relationship between high socioeconomic status and risk of developing exocrine pancreatic cancer.
AB - Objective: To investigate the relationship between socioeconomic characteristics, life style (coffee, alcohol and tobacco consumption), diabetes mellitus, first-degree family history of cancer and risk of exocrine pancreatic cancer. Design: Hospital-based case-control study. Methods: One hundred and fifty patients with exocrine panceatic cancer and 160 hospital controls were interviewed by trained personnel when still in hospital. Results: A statistically significant trend of increased risk of exocrine pancreatic cancer with a higher level of education was observed [relative risk (RR) = 1.55, confidence interval (Q) 1.10–2.19]. No association with other social characteristics (marital status, occupation and place of residence) and coffee, alcohol and tobacco consumption was found. There was a significantly increased risk of exocrine pancreatic cancer as the weekly consumption of spirits increased (RR = 1.52, Cl 1.06–2.19). Diabetes was associated with an increased risk of exocrine pancreatic cancer only when diagnosed less than 1 year prior to the interview (RR = 8.14, Cl 2.19–30.4). Conclusions: Our study confirms that there is an increased risk of exocrine pancreatic cancer associated with alcohol consumption. In addition, we observed a relationship between high socioeconomic status and risk of developing exocrine pancreatic cancer.
KW - Case-control study
KW - Exocrine pancreatic cancer
KW - Risk factors
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M3 - Article
AN - SCOPUS:0027278263
SN - 0954-691X
VL - 5
SP - 367
EP - 371
JO - European Journal of Gastroenterology and Hepatology
JF - European Journal of Gastroenterology and Hepatology
IS - 5
ER -