Sleep disorders in neurodegenerative diseases

A. Raggi, R. Ferri

Research output: Contribution to journalArticlepeer-review


The aim of this review is to provide data on sleep disturbances in three categories of neurodegenerative disorders: synucleinopathies, tauopathies, and other diseases (this heterogeneous group includes also spinocerebellar degeneration and amyotrophic lateral sclerosis). Analysing and knowing sleep disorders in neurodegenerative diseases may offer important insights into the pathomechanism of some of these diseases and calls attention to the still insufficiently known 'sleep neurology'. The identification of sleep disorders in some neurodegenerative conditions may make their diagnosis easier and earlier; for example, rapid eye movements sleep behaviour disorder may precede any other clinical manifestation of synucleinopathies by more than 10 years.

Original languageEnglish
Pages (from-to)1326-1338
Number of pages13
JournalEuropean Journal of Neurology
Issue number11
Publication statusPublished - Nov 2010


  • Neurodegenerative diseases
  • Pathophysiology
  • REM sleep behaviour disorder
  • Sleep disorders
  • Synucleinopathy
  • Tauopathy

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology


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