TY - JOUR
T1 - Simplifying clinical risk prediction for percutaneous coronary intervention of bifurcation lesions
T2 - The case for the ACEF (age, creatinine, ejection fraction) score
AU - Biondi-Zoccai, Giuseppe
AU - Romagnoli, Enrico
AU - Castagno, Davide
AU - Sheiban, Imad
AU - De Servi, Stefano
AU - Tamburino, Corrado
AU - Colombo, Antonio
AU - Burzotta, Francesco
AU - Presbitero, Patrizia
AU - Bolognese, Leonardo
AU - Paloscia, Leonardo
AU - Rubino, Paolo
AU - Sardella, Gennaro
AU - Briguori, Carlo
AU - Niccoli, Luigi
AU - Franco, Gianfranco
AU - Di Girolamo, Domenico D.
AU - Piatti, Luigi
AU - Greco, Cesare
AU - Petronio, A. Sonia
AU - Loi, Bruno
AU - Benassi, Alberto
AU - Patti, Aldo
AU - Gaspardone, Achille
AU - Frati, Giacomo
AU - Sangiorgi, Giuseppe
PY - 2012/7
Y1 - 2012/7
N2 - Aims: We aimed to appraise the predictive accuracy of a novel and user-friendly risk score, the ACEF (age, creatinine, ejection fraction), in patients undergoing PCI for coronary bifurcations. Methods and results: A multicentre, retrospective study was conducted enrolling consecutive patients undergoing bifurcation PCI between January 2002 and December 2006 in 22 Italian centres. Patients with complete data to enable computation of the ACEF score were divided into three groups according to tertiles of ACEF score. The primary endpoint was 30-day mortality. The discrimination of the ACEF score as a continuous variable was also appraised with area under the curve (AUC) of the receiver-operating characteristic. A total of 3,535 patients were included: 1,119 in the lowest tertile of ACEF score, 1,190 in the mid tertile, and 1,153 in the highest tertile. Increased ACEF score was associated with significantly different rates of 30-day mortality (0.1% in the lowest tertile vs. 0.5% in the mid tertile and 3.0% in the highest tertile, p
AB - Aims: We aimed to appraise the predictive accuracy of a novel and user-friendly risk score, the ACEF (age, creatinine, ejection fraction), in patients undergoing PCI for coronary bifurcations. Methods and results: A multicentre, retrospective study was conducted enrolling consecutive patients undergoing bifurcation PCI between January 2002 and December 2006 in 22 Italian centres. Patients with complete data to enable computation of the ACEF score were divided into three groups according to tertiles of ACEF score. The primary endpoint was 30-day mortality. The discrimination of the ACEF score as a continuous variable was also appraised with area under the curve (AUC) of the receiver-operating characteristic. A total of 3,535 patients were included: 1,119 in the lowest tertile of ACEF score, 1,190 in the mid tertile, and 1,153 in the highest tertile. Increased ACEF score was associated with significantly different rates of 30-day mortality (0.1% in the lowest tertile vs. 0.5% in the mid tertile and 3.0% in the highest tertile, p
KW - Bifurcation
KW - Coronary artery disease
KW - Prognosis
KW - Risk score
KW - Stent
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UR - http://www.scopus.com/inward/citedby.url?scp=84872060659&partnerID=8YFLogxK
U2 - 10.4244/EIJV8I3A55
DO - 10.4244/EIJV8I3A55
M3 - Article
C2 - 22584142
AN - SCOPUS:84872060659
SN - 1774-024X
VL - 8
SP - 359
EP - 367
JO - EuroIntervention
JF - EuroIntervention
IS - 3
ER -