Short term neurophysiological monitoring in multiple sclerosis bouts. Evaluation of steroid treatment

V. Scaioli; C. Milanese; A. Salmaggi; L. LaMantia; A. Campi; M. Eoli; F. Panzica

doi:10.1007/BF02226957

Short term neurophysiological monitoring in multiple sclerosis bouts. Evaluation of steroid treatment

V. Scaioli, C. Milanese, A. Salmaggi, L. LaMantia, A. Campi, M. Eoli, F. Panzica

Fondazione IRCCS Istituto Neurologico "C. Besta"

Research output: Contribution to journal › Article › peer-review

Abstract

Visual (VEP) and brainstem auditory (BAEP) evoked potentials (EP) were recorded in 21 multiple sclerosis (MS) patients in acute relapse before and after steroid treatment. VEPs were abnormal in 14/21 patients and BAEPs in 10/21 patients before treatment. In 4 patients with acute optic neuritis (ON), an improvement of VEPs paralleled clinical evolution in 3 cases. Substantial and contrasting changes in VEPs or BAEPs, with no clinical counterpart, were related to a spontaneous fluctuation of EPs in acute relapses of MS. These changes suggest frequent subclinical (multifocal and, possibly, sequential) central nervous system involvement in MS bouts. Group analysis showed nonsignificant changes in EP parameters before and after treatment. Our results indicate that evoked potentials (EPs) are of limited value for monitoring the short-term effect of steroid treatment in MS in bouts.

Original language	English
Pages (from-to)	107-112
Number of pages	6
Journal	Italian Journal of Neurological Sciences
Volume	13
Issue number	2
DOIs	https://doi.org/10.1007/BF02226957
Publication status	Published - Mar 1992

Keywords

evoked potentials
monitoring
Multiple sclerosis
treatment

ASJC Scopus subject areas

Neuroscience(all)
Clinical Neurology

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10.1007/BF02226957

Cite this

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title = "Short term neurophysiological monitoring in multiple sclerosis bouts. Evaluation of steroid treatment",

abstract = "Visual (VEP) and brainstem auditory (BAEP) evoked potentials (EP) were recorded in 21 multiple sclerosis (MS) patients in acute relapse before and after steroid treatment. VEPs were abnormal in 14/21 patients and BAEPs in 10/21 patients before treatment. In 4 patients with acute optic neuritis (ON), an improvement of VEPs paralleled clinical evolution in 3 cases. Substantial and contrasting changes in VEPs or BAEPs, with no clinical counterpart, were related to a spontaneous fluctuation of EPs in acute relapses of MS. These changes suggest frequent subclinical (multifocal and, possibly, sequential) central nervous system involvement in MS bouts. Group analysis showed nonsignificant changes in EP parameters before and after treatment. Our results indicate that evoked potentials (EPs) are of limited value for monitoring the short-term effect of steroid treatment in MS in bouts.",

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AU - Scaioli, V.

AU - Milanese, C.

AU - Salmaggi, A.

AU - LaMantia, L.

AU - Campi, A.

AU - Eoli, M.

AU - Panzica, F.

PY - 1992/3

Y1 - 1992/3

N2 - Visual (VEP) and brainstem auditory (BAEP) evoked potentials (EP) were recorded in 21 multiple sclerosis (MS) patients in acute relapse before and after steroid treatment. VEPs were abnormal in 14/21 patients and BAEPs in 10/21 patients before treatment. In 4 patients with acute optic neuritis (ON), an improvement of VEPs paralleled clinical evolution in 3 cases. Substantial and contrasting changes in VEPs or BAEPs, with no clinical counterpart, were related to a spontaneous fluctuation of EPs in acute relapses of MS. These changes suggest frequent subclinical (multifocal and, possibly, sequential) central nervous system involvement in MS bouts. Group analysis showed nonsignificant changes in EP parameters before and after treatment. Our results indicate that evoked potentials (EPs) are of limited value for monitoring the short-term effect of steroid treatment in MS in bouts.

AB - Visual (VEP) and brainstem auditory (BAEP) evoked potentials (EP) were recorded in 21 multiple sclerosis (MS) patients in acute relapse before and after steroid treatment. VEPs were abnormal in 14/21 patients and BAEPs in 10/21 patients before treatment. In 4 patients with acute optic neuritis (ON), an improvement of VEPs paralleled clinical evolution in 3 cases. Substantial and contrasting changes in VEPs or BAEPs, with no clinical counterpart, were related to a spontaneous fluctuation of EPs in acute relapses of MS. These changes suggest frequent subclinical (multifocal and, possibly, sequential) central nervous system involvement in MS bouts. Group analysis showed nonsignificant changes in EP parameters before and after treatment. Our results indicate that evoked potentials (EPs) are of limited value for monitoring the short-term effect of steroid treatment in MS in bouts.

KW - evoked potentials

KW - monitoring

KW - Multiple sclerosis

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Short term neurophysiological monitoring in multiple sclerosis bouts. Evaluation of steroid treatment

Abstract

Keywords

ASJC Scopus subject areas

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