Serial study of neuropsychological performance and gadolinium-enhanced MRI in MS

F. Mattioli, S. F. Cappa, C. Cominelli, R. Capra, N. Marcianoc, R. Gasparotti

Research output: Contribution to journalArticlepeer-review


Many multiple sclerosis patients show cognitive decline, although no definite correlation between brain demyelination at MRI and neuropsychological performance has been found so far. We submitted a group of nine relapsing-remitting, mildly disabled patients to both serial gadolinium-DTPA enhanced MRI and neuropsychological evaluation in a follow up period of three months. Despite the great variability in acute lesions' load, no overall decline in test, performance was found. Furthermore, in selected cases whose test scores declined at follow up, no concordance with the new lesion load was found.

Original languageEnglish
Pages (from-to)465-468
Number of pages4
JournalActa Neurologica Scandinavica
Issue number6
Publication statusPublished - 1993


  • gadolinium-DTPA enhanced MRI
  • multiple sclerosis
  • neuropsychological impairment

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)


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