Sepsis in head and neck cancer patients treated with chemotherapy and radiation: Literature review and consensus

Aurora Mirabile, Gianmauro Numico, Elvio G. Russi, Paolo Bossi, Fulvio Crippa, Almalina Bacigalupo, Vitaliana De Sanctis, Stefania Musso, Anna Merlotti, Maria Grazia Ghi, Marco C. Merlano, Lisa Licitra, Francesco Moretto, Nerina Denaro, Orietta Caspiani, Michela Buglione, Stefano Pergolizzi, Antonio Cascio, Jacques Bernier, Judith Raber-DurlacherJan B. Vermorken, Barbara Murphy, Marco V. Ranieri, R. Phillip Dellinger

Research output: Contribution to journalArticlepeer-review

Abstract

The reporting of infection/sepsis in chemo/radiation-treated head and neck cancer patients is sparse and the problem is underestimated. A multidisciplinary group of head and neck cancer specialists from Italy met with the aim of reaching a consensus on a clinical definition and management of infections and sepsis. The Delphi appropriateness method was used for this consensus. External expert reviewers then evaluated the conclusions carefully according to their area of expertise. The paper contains seven clusters of statements about the clinical definition and management of infections and sepsis in head and neck cancer patients, which had a consensus. Furthermore, it offers a review of recent literature in these topics.

Original languageEnglish
Pages (from-to)191-213
Number of pages23
JournalCritical Reviews in Oncology/Hematology
Volume95
Issue number2
DOIs
Publication statusPublished - Aug 1 2015

Keywords

  • Chemotherapy
  • Head and neck cancer
  • Radiotherapy
  • Sepsis

ASJC Scopus subject areas

  • Oncology
  • Hematology
  • Geriatrics and Gerontology

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