Sensory (VEP, BAEP, SEP) and motor–evoked potentials, liquoral and magnetic resonance findings in multiple sclerosis

Paolo M. Rossini; F. Zarola; R. Floris; G. Bernardi; A. Perretti; L. Pelosi; G. Caruso; M. D. Caramia

doi:10.1159/000116376

Sensory (VEP, BAEP, SEP) and motor–evoked potentials, liquoral and magnetic resonance findings in multiple sclerosis

Paolo M. Rossini, F. Zarola, R. Floris, G. Bernardi, A. Perretti, L. Pelosi, G. Caruso, M. D. Caramia

Research output: Contribution to journal › Article › peer-review

Abstract

In order to define the most suitable instrumental protocol for the diagnosis of multiple sclerosis (MS), 41 patients with definite (D = 14), probable (P = 14) and suspected (S = 13) MS were examined with CSF immunology, brain MRI and multimodal evoked potentials. The central motor tracts were also tested. The following alteration rates were found: MRI = 78%, CSF = 63.6%, VEP = 70.0%, median nerve SEP = 50%, peroneal nerve SEP = 68.0%, BAEPs = 35.7%, motor-evoked potentials (MEPs) = 74.0%. Altogether, EPs were abnormal in 90% of cases. Normal MRI with altered EPs were found in 22% of cases, whilst a normal EP battery with defective CSF or MRI findings were found in 7%. Twenty-six out of 27 patients with P or S forms were reclassified into a D one when considering EPs and MRI features.

Original language	English
Pages (from-to)	41-47
Number of pages	7
Journal	European Neurology
Volume	29
Issue number	1
DOIs	https://doi.org/10.1159/000116376
Publication status	Published - 1989

Keywords

Evoked potentials
Magnetic resonance
Multiple sclerosis

ASJC Scopus subject areas

Clinical Neurology
Neurology

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10.1159/000116376

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title = "Sensory (VEP, BAEP, SEP) and motor–evoked potentials, liquoral and magnetic resonance findings in multiple sclerosis",

abstract = "In order to define the most suitable instrumental protocol for the diagnosis of multiple sclerosis (MS), 41 patients with definite (D = 14), probable (P = 14) and suspected (S = 13) MS were examined with CSF immunology, brain MRI and multimodal evoked potentials. The central motor tracts were also tested. The following alteration rates were found: MRI = 78%, CSF = 63.6%, VEP = 70.0%, median nerve SEP = 50%, peroneal nerve SEP = 68.0%, BAEPs = 35.7%, motor-evoked potentials (MEPs) = 74.0%. Altogether, EPs were abnormal in 90% of cases. Normal MRI with altered EPs were found in 22% of cases, whilst a normal EP battery with defective CSF or MRI findings were found in 7%. Twenty-six out of 27 patients with P or S forms were reclassified into a D one when considering EPs and MRI features.",

keywords = "Evoked potentials, Magnetic resonance, Multiple sclerosis",

author = "Rossini, {Paolo M.} and F. Zarola and R. Floris and G. Bernardi and A. Perretti and L. Pelosi and G. Caruso and Caramia, {M. D.}",

year = "1989",

doi = "10.1159/000116376",

language = "English",

volume = "29",

pages = "41--47",

journal = "European Neurology",

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T1 - Sensory (VEP, BAEP, SEP) and motor–evoked potentials, liquoral and magnetic resonance findings in multiple sclerosis

AU - Rossini, Paolo M.

AU - Zarola, F.

AU - Floris, R.

AU - Bernardi, G.

AU - Perretti, A.

AU - Pelosi, L.

AU - Caruso, G.

AU - Caramia, M. D.

PY - 1989

Y1 - 1989

N2 - In order to define the most suitable instrumental protocol for the diagnosis of multiple sclerosis (MS), 41 patients with definite (D = 14), probable (P = 14) and suspected (S = 13) MS were examined with CSF immunology, brain MRI and multimodal evoked potentials. The central motor tracts were also tested. The following alteration rates were found: MRI = 78%, CSF = 63.6%, VEP = 70.0%, median nerve SEP = 50%, peroneal nerve SEP = 68.0%, BAEPs = 35.7%, motor-evoked potentials (MEPs) = 74.0%. Altogether, EPs were abnormal in 90% of cases. Normal MRI with altered EPs were found in 22% of cases, whilst a normal EP battery with defective CSF or MRI findings were found in 7%. Twenty-six out of 27 patients with P or S forms were reclassified into a D one when considering EPs and MRI features.

AB - In order to define the most suitable instrumental protocol for the diagnosis of multiple sclerosis (MS), 41 patients with definite (D = 14), probable (P = 14) and suspected (S = 13) MS were examined with CSF immunology, brain MRI and multimodal evoked potentials. The central motor tracts were also tested. The following alteration rates were found: MRI = 78%, CSF = 63.6%, VEP = 70.0%, median nerve SEP = 50%, peroneal nerve SEP = 68.0%, BAEPs = 35.7%, motor-evoked potentials (MEPs) = 74.0%. Altogether, EPs were abnormal in 90% of cases. Normal MRI with altered EPs were found in 22% of cases, whilst a normal EP battery with defective CSF or MRI findings were found in 7%. Twenty-six out of 27 patients with P or S forms were reclassified into a D one when considering EPs and MRI features.

KW - Evoked potentials

KW - Magnetic resonance

KW - Multiple sclerosis

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Sensory (VEP, BAEP, SEP) and motor–evoked potentials, liquoral and magnetic resonance findings in multiple sclerosis

Abstract

Keywords

ASJC Scopus subject areas

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